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Embolic events in 93 elderly Chinese patients with atrial fibrillation.
Chin Med J (Engl). 2000 Apr; 113(4):320-3.CM

Abstract

OBJECTIVES

To evaluate the prevalence of embolic events and relevant factors in elderly Chinese patients with atrial fibrillation(AF), and to provide evidence on ways to prevent embolic events.

METHODS

Autopsy data from ninety-three continous elderly Chinese patients with AF were analysed. The incidence of embolic events and its relationship to underlying disease, pathologic changes in the heart, and other clinical characteristics were examined.

RESULTS

Embolism were observed in 27 of 93 cases, with an incidence of 29.03%. The incidence of embolic events was higher in elderly patients with rheumatic heart disease than those with coronary artery disease, hypertensive myocardiopathy and heart diseases. Patients with chronic AF, with a course of AF > or = 3 years, and those with heart failure or diabetes had a higher incidence of embolic events than those without these complications. There was significant difference in incidence between paroxysmal and chronic AF. Patients with left atrial or ventricular enlargement, mural thrombosis in cardiac chambers, valvular calcification and valvular vegetation also had a higher incidence of embolic events. Oral dipyridamole (75-150 mg/d) or aspirin (50-150 mg/d) showed no definite effects in preventing embolism in some patients.

CONCLUSIONS

There was a high incidence of embolic events in elderly Chinese patients with AF. Anticoagulation therapy should be provided to the elderly patients with AF, especially to the patients with risk factors for embolism.

Authors+Show Affiliations

Department of Cardiology, 252th Hospital of PLA, Baoding 071000, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11775227

Citation

Cao, X, et al. "Embolic Events in 93 Elderly Chinese Patients With Atrial Fibrillation." Chinese Medical Journal, vol. 113, no. 4, 2000, pp. 320-3.
Cao X, Wang S, Jiang L, et al. Embolic events in 93 elderly Chinese patients with atrial fibrillation. Chin Med J (Engl). 2000;113(4):320-3.
Cao, X., Wang, S., Jiang, L., Liu, L., Huang, H., & Lu, Z. (2000). Embolic events in 93 elderly Chinese patients with atrial fibrillation. Chinese Medical Journal, 113(4), 320-3.
Cao X, et al. Embolic Events in 93 Elderly Chinese Patients With Atrial Fibrillation. Chin Med J (Engl). 2000;113(4):320-3. PubMed PMID: 11775227.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Embolic events in 93 elderly Chinese patients with atrial fibrillation. AU - Cao,X, AU - Wang,S, AU - Jiang,L, AU - Liu,L, AU - Huang,H, AU - Lu,Z, PY - 2002/1/5/pubmed PY - 2002/2/8/medline PY - 2002/1/5/entrez SP - 320 EP - 3 JF - Chinese medical journal JO - Chin Med J (Engl) VL - 113 IS - 4 N2 - OBJECTIVES: To evaluate the prevalence of embolic events and relevant factors in elderly Chinese patients with atrial fibrillation(AF), and to provide evidence on ways to prevent embolic events. METHODS: Autopsy data from ninety-three continous elderly Chinese patients with AF were analysed. The incidence of embolic events and its relationship to underlying disease, pathologic changes in the heart, and other clinical characteristics were examined. RESULTS: Embolism were observed in 27 of 93 cases, with an incidence of 29.03%. The incidence of embolic events was higher in elderly patients with rheumatic heart disease than those with coronary artery disease, hypertensive myocardiopathy and heart diseases. Patients with chronic AF, with a course of AF > or = 3 years, and those with heart failure or diabetes had a higher incidence of embolic events than those without these complications. There was significant difference in incidence between paroxysmal and chronic AF. Patients with left atrial or ventricular enlargement, mural thrombosis in cardiac chambers, valvular calcification and valvular vegetation also had a higher incidence of embolic events. Oral dipyridamole (75-150 mg/d) or aspirin (50-150 mg/d) showed no definite effects in preventing embolism in some patients. CONCLUSIONS: There was a high incidence of embolic events in elderly Chinese patients with AF. Anticoagulation therapy should be provided to the elderly patients with AF, especially to the patients with risk factors for embolism. SN - 0366-6999 UR - https://www.unboundmedicine.com/medline/citation/11775227/Embolic_events_in_93_elderly_Chinese_patients_with_atrial_fibrillation_ L2 - https://medlineplus.gov/atrialfibrillation.html DB - PRIME DP - Unbound Medicine ER -