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[Expression of bcl-2 protein in adenomyosis].
Zhonghua Fu Chan Ke Za Zhi. 2000 Sep; 35(9):533-5.ZF

Abstract

OBJECTIVE

To investigate the expression of B cell lymphoma/leukemia-2 (Bcl-2) protein in adenomyosis and its clinical implication.

METHODS

Endometrium specimens were obtained from 16 normal uterus and 32 with adenomyosis. bcl-2 expression in these paraffin embraced specimens was examined by immunohistochemical technique with specific monoclonal antibodies.

RESULTS

bcl-2 expression in normal endometrium showed a significant cyclic variation. bcl-2 expression of glandular cells in both eutopic and ectopic endometrium of adenomyosis also showed a significant cyclic variation. bcl-2 expression in endometrium of adenomyosis was stronger than that in normal endometrium, and bcl-2 expression in ectopic endometrium was stronger than that in eutopic endometrium.

CONCLUSION

The decrease of cellular apoptosis resulted from the high bcl-2 expression may play an important role in the pathogenesis of adenomyosis.

Authors+Show Affiliations

Department of Reproductive Medical Research, Shandong Family Planning Institute, Jinan 250002, China.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

11775943

Citation

Zhang, L, et al. "[Expression of Bcl-2 Protein in Adenomyosis]." Zhonghua Fu Chan Ke Za Zhi, vol. 35, no. 9, 2000, pp. 533-5.
Zhang L, Li J, Li M. [Expression of bcl-2 protein in adenomyosis]. Zhonghua Fu Chan Ke Za Zhi. 2000;35(9):533-5.
Zhang, L., Li, J., & Li, M. (2000). [Expression of bcl-2 protein in adenomyosis]. Zhonghua Fu Chan Ke Za Zhi, 35(9), 533-5.
Zhang L, Li J, Li M. [Expression of Bcl-2 Protein in Adenomyosis]. Zhonghua Fu Chan Ke Za Zhi. 2000;35(9):533-5. PubMed PMID: 11775943.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Expression of bcl-2 protein in adenomyosis]. AU - Zhang,L, AU - Li,J, AU - Li,M, PY - 2002/1/5/pubmed PY - 2002/1/31/medline PY - 2002/1/5/entrez SP - 533 EP - 5 JF - Zhonghua fu chan ke za zhi JO - Zhonghua Fu Chan Ke Za Zhi VL - 35 IS - 9 N2 - OBJECTIVE: To investigate the expression of B cell lymphoma/leukemia-2 (Bcl-2) protein in adenomyosis and its clinical implication. METHODS: Endometrium specimens were obtained from 16 normal uterus and 32 with adenomyosis. bcl-2 expression in these paraffin embraced specimens was examined by immunohistochemical technique with specific monoclonal antibodies. RESULTS: bcl-2 expression in normal endometrium showed a significant cyclic variation. bcl-2 expression of glandular cells in both eutopic and ectopic endometrium of adenomyosis also showed a significant cyclic variation. bcl-2 expression in endometrium of adenomyosis was stronger than that in normal endometrium, and bcl-2 expression in ectopic endometrium was stronger than that in eutopic endometrium. CONCLUSION: The decrease of cellular apoptosis resulted from the high bcl-2 expression may play an important role in the pathogenesis of adenomyosis. SN - 0529-567X UR - https://www.unboundmedicine.com/medline/citation/11775943/[Expression_of_bcl_2_protein_in_adenomyosis]_ L2 - http://www.diseaseinfosearch.org/result/226 DB - PRIME DP - Unbound Medicine ER -
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