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Methoxylated xanthones in the quality control of small centaury (Centaurium erythraea) flowering tops.
J Agric Food Chem. 2002 Jan 30; 50(3):460-3.JA

Abstract

In the course of a phytochemical study of the bitter tonic plant, small centaury (Centaurium erythraea), six methoxylated xanthones (1,5-hydroxy-3-methoxyxanthone, 1-hydroxy-3,5,6-trimethoxyxanthone, 1-hydroxy-3,5,6,7-tetramethoxyxanthone, 1-hydroxy-3,5,6,7,8-pentamethoxyxanthone, 1-hydroxy-3,7,8-trimethoxyxanthone and 1,8-dihydroxy-3,5,6,7-tetramethoxyxanthone) were isolated and identified by spectroscopic means (nuclear magnetic resonance, mass spectroscopy, and UV). Subsequently, a high-performance liquid chromatography/diode array detection method was developed for the determination of these and other methoxylated xanthones occurring in the chloroform extract of small centaury aerial parts. The methodology developed was applied to twelve samples, and in all of them, nine xanthones were identified and quantified. This methodology can be considered complimentary to the one proposed by the European Pharmacopoeia.

Authors+Show Affiliations

CEQUP/Serviço de Farmacognosia, Faculdade de Farmácia, Universidade do Porto, R. Aníbal Cunha, 4050-047 Porto, Portugal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11804512

Citation

Valentão, Patrícia, et al. "Methoxylated Xanthones in the Quality Control of Small Centaury (Centaurium Erythraea) Flowering Tops." Journal of Agricultural and Food Chemistry, vol. 50, no. 3, 2002, pp. 460-3.
Valentão P, Andrade PB, Silva E, et al. Methoxylated xanthones in the quality control of small centaury (Centaurium erythraea) flowering tops. J Agric Food Chem. 2002;50(3):460-3.
Valentão, P., Andrade, P. B., Silva, E., Vicente, A., Santos, H., Bastos, M. L., & Seabra, R. M. (2002). Methoxylated xanthones in the quality control of small centaury (Centaurium erythraea) flowering tops. Journal of Agricultural and Food Chemistry, 50(3), 460-3.
Valentão P, et al. Methoxylated Xanthones in the Quality Control of Small Centaury (Centaurium Erythraea) Flowering Tops. J Agric Food Chem. 2002 Jan 30;50(3):460-3. PubMed PMID: 11804512.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Methoxylated xanthones in the quality control of small centaury (Centaurium erythraea) flowering tops. AU - Valentão,Patrícia, AU - Andrade,Paula B, AU - Silva,Eurico, AU - Vicente,Ana, AU - Santos,Henrique, AU - Bastos,M Lourdes, AU - Seabra,Rosa M, PY - 2002/1/24/pubmed PY - 2002/5/25/medline PY - 2002/1/24/entrez SP - 460 EP - 3 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 50 IS - 3 N2 - In the course of a phytochemical study of the bitter tonic plant, small centaury (Centaurium erythraea), six methoxylated xanthones (1,5-hydroxy-3-methoxyxanthone, 1-hydroxy-3,5,6-trimethoxyxanthone, 1-hydroxy-3,5,6,7-tetramethoxyxanthone, 1-hydroxy-3,5,6,7,8-pentamethoxyxanthone, 1-hydroxy-3,7,8-trimethoxyxanthone and 1,8-dihydroxy-3,5,6,7-tetramethoxyxanthone) were isolated and identified by spectroscopic means (nuclear magnetic resonance, mass spectroscopy, and UV). Subsequently, a high-performance liquid chromatography/diode array detection method was developed for the determination of these and other methoxylated xanthones occurring in the chloroform extract of small centaury aerial parts. The methodology developed was applied to twelve samples, and in all of them, nine xanthones were identified and quantified. This methodology can be considered complimentary to the one proposed by the European Pharmacopoeia. SN - 0021-8561 UR - https://www.unboundmedicine.com/medline/citation/11804512/Methoxylated_xanthones_in_the_quality_control_of_small_centaury__Centaurium_erythraea__flowering_tops_ L2 - https://doi.org/10.1021/jf0109571 DB - PRIME DP - Unbound Medicine ER -