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Risk factors and seroprevalence of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus infection in uzbekistan.
Intervirology. 2001; 44(6):327-32.I

Abstract

OBJECTIVES

The aim of this study was to elucidate the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infection in Uzbekistan and to explore whether there is a correlation between those blood-borne agents and socioeconomic risk factors.

METHODS

One thousand nine hundred and eighteen subjects were studied. The subjects were divided into a low-risk group, a high-risk group and a patient group. Sera were tested for HBV surface antigen (HBsAg), anti-HCV, and anti-HIV.

RESULTS

The seroprevalence of HBsAg, anti-HCV, and anti-HIV in the general population was 13.3, 13.1 and 0%, respectively. The anti-HCV infection rate was significantly higher in intravenous drug users (62.7%) than in prostitutes (9.2%), homosexuals (11.1%), and medical laboratory employees (12.5%) (p < 0.01). In the low-risk group, positivity for anti-HCV increased with age from 2.2% in the 15- to 20-year-olds up to the highest rate of 17.6% in the 31- to 40-year-olds; the positivity then decreased to 0% in the group over 60 years of age. In the high-risk group, the positivity for anti-HCV in the age groups under 40 years was approximately 30% and significantly higher than in the low-risk group (p < 0.01). Risk factors for transmission of HCV were medical treatment in the low-risk group, drug abuse in the high-risk group, and both in the patient group.

CONCLUSIONS

This study demonstrates that the seroprevalence of HBV and HCV infection is high, whereas HIV infection is yet uncommon in Uzbekistan.

Authors+Show Affiliations

Institute of Immunology, Academy of Science, Tashkent, Uzbekistan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11805437

Citation

Ruzibakiev, R, et al. "Risk Factors and Seroprevalence of Hepatitis B Virus, Hepatitis C Virus, and Human Immunodeficiency Virus Infection in Uzbekistan." Intervirology, vol. 44, no. 6, 2001, pp. 327-32.
Ruzibakiev R, Kato H, Ueda R, et al. Risk factors and seroprevalence of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus infection in uzbekistan. Intervirology. 2001;44(6):327-32.
Ruzibakiev, R., Kato, H., Ueda, R., Yuldasheva, N., Hegay, T., Avazova, D., Kurbanov, F., Zalalieva, M., Tuichiev, L., Achundjanov, B., & Mizokami, M. (2001). Risk factors and seroprevalence of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus infection in uzbekistan. Intervirology, 44(6), 327-32.
Ruzibakiev R, et al. Risk Factors and Seroprevalence of Hepatitis B Virus, Hepatitis C Virus, and Human Immunodeficiency Virus Infection in Uzbekistan. Intervirology. 2001;44(6):327-32. PubMed PMID: 11805437.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors and seroprevalence of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus infection in uzbekistan. AU - Ruzibakiev,R, AU - Kato,H, AU - Ueda,R, AU - Yuldasheva,N, AU - Hegay,T, AU - Avazova,D, AU - Kurbanov,F, AU - Zalalieva,M, AU - Tuichiev,L, AU - Achundjanov,B, AU - Mizokami,M, PY - 2002/1/24/pubmed PY - 2002/4/3/medline PY - 2002/1/24/entrez SP - 327 EP - 32 JF - Intervirology JO - Intervirology VL - 44 IS - 6 N2 - OBJECTIVES: The aim of this study was to elucidate the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infection in Uzbekistan and to explore whether there is a correlation between those blood-borne agents and socioeconomic risk factors. METHODS: One thousand nine hundred and eighteen subjects were studied. The subjects were divided into a low-risk group, a high-risk group and a patient group. Sera were tested for HBV surface antigen (HBsAg), anti-HCV, and anti-HIV. RESULTS: The seroprevalence of HBsAg, anti-HCV, and anti-HIV in the general population was 13.3, 13.1 and 0%, respectively. The anti-HCV infection rate was significantly higher in intravenous drug users (62.7%) than in prostitutes (9.2%), homosexuals (11.1%), and medical laboratory employees (12.5%) (p < 0.01). In the low-risk group, positivity for anti-HCV increased with age from 2.2% in the 15- to 20-year-olds up to the highest rate of 17.6% in the 31- to 40-year-olds; the positivity then decreased to 0% in the group over 60 years of age. In the high-risk group, the positivity for anti-HCV in the age groups under 40 years was approximately 30% and significantly higher than in the low-risk group (p < 0.01). Risk factors for transmission of HCV were medical treatment in the low-risk group, drug abuse in the high-risk group, and both in the patient group. CONCLUSIONS: This study demonstrates that the seroprevalence of HBV and HCV infection is high, whereas HIV infection is yet uncommon in Uzbekistan. SN - 0300-5526 UR - https://www.unboundmedicine.com/medline/citation/11805437/Risk_factors_and_seroprevalence_of_hepatitis_B_virus_hepatitis_C_virus_and_human_immunodeficiency_virus_infection_in_uzbekistan_ L2 - https://www.karger.com?DOI=10.1159/000050066 DB - PRIME DP - Unbound Medicine ER -