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Antifungal activity of benzoic acid derivatives from Piper lanceaefolium.
J Nat Prod. 2002 Jan; 65(1):62-4.JN

Abstract

Bioactivity-guided fractionation of a methanol extract from the leaves of Piper lanceaefolium resulted in the isolation of four new benzoic acid derivatives (1-4), together with taboganic acid, pinocembrin, and pinocembrin chalcone. Lanceaefolic acid methyl ester (3) and pinocembrin chalcone displayed activity against Candida albicans with a minimal inhibitory concentration value of 100 microg/mL in both cases.

Authors+Show Affiliations

López A
Department of Botany, University of British Columbia, #3529-6270 University Boulevard, Vancouver, B.C., Canada V6T 1Z4.
Ming DS
No affiliation info available
Towers GH
No affiliation info available

MeSH

Antifungal AgentsBenzoatesCandida albicansChromatography, Thin LayerColombiaFlavanonesFlavonoidsMolecular ConformationMolecular StructureNuclear Magnetic Resonance, BiomolecularPiperaceaePlant LeavesPlants, MedicinalSpectrophotometry, InfraredSpectrophotometry, UltravioletToxicity Tests

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11809068

Citation

López, Andrés, et al. "Antifungal Activity of Benzoic Acid Derivatives From Piper Lanceaefolium." Journal of Natural Products, vol. 65, no. 1, 2002, pp. 62-4.
López A, Ming DS, Towers GH. Antifungal activity of benzoic acid derivatives from Piper lanceaefolium. J Nat Prod. 2002;65(1):62-4.
López, A., Ming, D. S., & Towers, G. H. (2002). Antifungal activity of benzoic acid derivatives from Piper lanceaefolium. Journal of Natural Products, 65(1), 62-4.
López A, Ming DS, Towers GH. Antifungal Activity of Benzoic Acid Derivatives From Piper Lanceaefolium. J Nat Prod. 2002;65(1):62-4. PubMed PMID: 11809068.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antifungal activity of benzoic acid derivatives from Piper lanceaefolium. AU - López,Andrés, AU - Ming,Dong Sheng, AU - Towers,G H Neil, PY - 2002/1/26/pubmed PY - 2002/3/27/medline PY - 2002/1/26/entrez SP - 62 EP - 4 JF - Journal of natural products JO - J Nat Prod VL - 65 IS - 1 N2 - Bioactivity-guided fractionation of a methanol extract from the leaves of Piper lanceaefolium resulted in the isolation of four new benzoic acid derivatives (1-4), together with taboganic acid, pinocembrin, and pinocembrin chalcone. Lanceaefolic acid methyl ester (3) and pinocembrin chalcone displayed activity against Candida albicans with a minimal inhibitory concentration value of 100 microg/mL in both cases. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/11809068/Antifungal_activity_of_benzoic_acid_derivatives_from_Piper_lanceaefolium_ L2 - https://doi.org/10.1021/np010410g DB - PRIME DP - Unbound Medicine ER -