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[Kidney lesion in mice from an antirenal serum].
Arkh Patol 1975; 37(7):56-61AP

Abstract

Intravenous administration of anti-renal serum in a dose 1--1.6 ml to mice line CBA brought about drastic changes in the kidney ranging from severe dystrophy of the tubule cells to necrosis of the epithelium of the proximal and straight tubules. A smaller dose (0.5 ml) produced initially degenerative changes in individual cells of the proximal convoluted and straight tubules, and 2--6 months later degenerative changes were noted almost in all cells of the tubules referred to above. The glomerular apparatus was affected in a lesser degree. The relative weight of the kidneys of the mice treated with anti-renal serum at the end of the 3rd month was less than that in control animals. The urine contained granular and hyaline cylinders and a considerable amount of protein. Concentration of urea in the blood serum of the experimental animals was found to be elevated.

Authors

No affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

1182048

Citation

Averkina, R F.. "[Kidney Lesion in Mice From an Antirenal Serum]." Arkhiv Patologii, vol. 37, no. 7, 1975, pp. 56-61.
Averkina RF. [Kidney lesion in mice from an antirenal serum]. Arkh Patol. 1975;37(7):56-61.
Averkina, R. F. (1975). [Kidney lesion in mice from an antirenal serum]. Arkhiv Patologii, 37(7), pp. 56-61.
Averkina RF. [Kidney Lesion in Mice From an Antirenal Serum]. Arkh Patol. 1975;37(7):56-61. PubMed PMID: 1182048.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Kidney lesion in mice from an antirenal serum]. A1 - Averkina,R F, PY - 1975/1/1/pubmed PY - 1975/1/1/medline PY - 1975/1/1/entrez SP - 56 EP - 61 JF - Arkhiv patologii JO - Arkh. Patol. VL - 37 IS - 7 N2 - Intravenous administration of anti-renal serum in a dose 1--1.6 ml to mice line CBA brought about drastic changes in the kidney ranging from severe dystrophy of the tubule cells to necrosis of the epithelium of the proximal and straight tubules. A smaller dose (0.5 ml) produced initially degenerative changes in individual cells of the proximal convoluted and straight tubules, and 2--6 months later degenerative changes were noted almost in all cells of the tubules referred to above. The glomerular apparatus was affected in a lesser degree. The relative weight of the kidneys of the mice treated with anti-renal serum at the end of the 3rd month was less than that in control animals. The urine contained granular and hyaline cylinders and a considerable amount of protein. Concentration of urea in the blood serum of the experimental animals was found to be elevated. SN - 0004-1955 UR - https://www.unboundmedicine.com/medline/citation/1182048/[Kidney_lesion_in_mice_from_an_antirenal_serum]_ L2 - https://medlineplus.gov/kidneydiseases.html DB - PRIME DP - Unbound Medicine ER -