Tags

Type your tag names separated by a space and hit enter

The pathology of human and murine pulmonary infection with Cryptococcus neoformans var. gattii.
Pathology. 2001 Nov; 33(4):475-8.P

Abstract

Human infection by Cryptococcus neoformans var. neoformans is well characterised and usually occurs in immunocompromised patients. Less is known about infection by Cryptococcus neoformans var. gattii, which usually produces disease in previously normal individuals. In two cases of human pulmonary infection by Cryptococcus neoformans var. gattii, we observed a mixed inflammatory pattern, including granulomas associated with numerous T lymphocytes and a lymphocytic interstitial pneumonitis with B lymphocytes and formation of follicles. We also established a murine model of pulmonary infection by Cryptococcus neoformans var. gattii, which reproduced most of these features. This model is likely to prove useful in studies of the pathogenesis of this infection.

Authors+Show Affiliations

Inflammation Research Unit, School of Pathology, University of New South Wales, Randwick, Australia. A.Torda@unsw.edu.auNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11827415

Citation

Torda, A, et al. "The Pathology of Human and Murine Pulmonary Infection With Cryptococcus Neoformans Var. Gattii." Pathology, vol. 33, no. 4, 2001, pp. 475-8.
Torda A, Kumar RK, Jones PD. The pathology of human and murine pulmonary infection with Cryptococcus neoformans var. gattii. Pathology. 2001;33(4):475-8.
Torda, A., Kumar, R. K., & Jones, P. D. (2001). The pathology of human and murine pulmonary infection with Cryptococcus neoformans var. gattii. Pathology, 33(4), 475-8.
Torda A, Kumar RK, Jones PD. The Pathology of Human and Murine Pulmonary Infection With Cryptococcus Neoformans Var. Gattii. Pathology. 2001;33(4):475-8. PubMed PMID: 11827415.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The pathology of human and murine pulmonary infection with Cryptococcus neoformans var. gattii. AU - Torda,A, AU - Kumar,R K, AU - Jones,P D, PY - 2002/2/6/pubmed PY - 2002/7/10/medline PY - 2002/2/6/entrez SP - 475 EP - 8 JF - Pathology JO - Pathology VL - 33 IS - 4 N2 - Human infection by Cryptococcus neoformans var. neoformans is well characterised and usually occurs in immunocompromised patients. Less is known about infection by Cryptococcus neoformans var. gattii, which usually produces disease in previously normal individuals. In two cases of human pulmonary infection by Cryptococcus neoformans var. gattii, we observed a mixed inflammatory pattern, including granulomas associated with numerous T lymphocytes and a lymphocytic interstitial pneumonitis with B lymphocytes and formation of follicles. We also established a murine model of pulmonary infection by Cryptococcus neoformans var. gattii, which reproduced most of these features. This model is likely to prove useful in studies of the pathogenesis of this infection. SN - 0031-3025 UR - https://www.unboundmedicine.com/medline/citation/11827415/The_pathology_of_human_and_murine_pulmonary_infection_with_Cryptococcus_neoformans_var__gattii_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=11827415.ui DB - PRIME DP - Unbound Medicine ER -