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Early clinical diagnosis of solitary plasmacytoma of the jaws: a case report with a six year follow-up.
Int J Oral Maxillofac Surg. 2001 Dec; 30(6):558-60.IJ

Abstract

The authors reported a case of a solitary mandibular plasmacytoma in a 53-year-old male Caucasian patient. The histological examination of the specimen was positive for a plasmacytoma with anaplastic appearance. Since the patient refused a demolitive surgical treatment, he was treated with a local radiation therapy of 4000 rads over a 20-day period and polychemotherapy with cyclophosphamide, prednisone and melphalan. Six years after starting radiation treatment the patient is free of recurrent primary disease and not affected by multiple localization. In conclusion, the solitary bone plasmacytoma represents an initial stage of the multiple myeloma rather than a distinct clinical pathology. Unfortunately, the diagnosis of the plasmacytoma is only rarely carried out in the early phases of the disease. The importance of the identification of the initial stage without a clear M component, as in the reported case, is self-evident, since the prognosis is related to the mass of plasmacytoma cells that are present at the time of the diagnosis. The purpose of this study is to report an extremely rare case of solitary bone plasmacytoma with a mandibular localization treated with radio- and polychemotherapy.

Authors+Show Affiliations

Institute of Dental Sciences, University of Ancona, Italy. lomuziol@tin.itNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11829241

Citation

Lo Muzio, L, et al. "Early Clinical Diagnosis of Solitary Plasmacytoma of the Jaws: a Case Report With a Six Year Follow-up." International Journal of Oral and Maxillofacial Surgery, vol. 30, no. 6, 2001, pp. 558-60.
Lo Muzio L, Pannone G, Bucci P. Early clinical diagnosis of solitary plasmacytoma of the jaws: a case report with a six year follow-up. Int J Oral Maxillofac Surg. 2001;30(6):558-60.
Lo Muzio, L., Pannone, G., & Bucci, P. (2001). Early clinical diagnosis of solitary plasmacytoma of the jaws: a case report with a six year follow-up. International Journal of Oral and Maxillofacial Surgery, 30(6), 558-60.
Lo Muzio L, Pannone G, Bucci P. Early Clinical Diagnosis of Solitary Plasmacytoma of the Jaws: a Case Report With a Six Year Follow-up. Int J Oral Maxillofac Surg. 2001;30(6):558-60. PubMed PMID: 11829241.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Early clinical diagnosis of solitary plasmacytoma of the jaws: a case report with a six year follow-up. AU - Lo Muzio,L, AU - Pannone,G, AU - Bucci,P, PY - 2002/2/7/pubmed PY - 2002/5/10/medline PY - 2002/2/7/entrez SP - 558 EP - 60 JF - International journal of oral and maxillofacial surgery JO - Int J Oral Maxillofac Surg VL - 30 IS - 6 N2 - The authors reported a case of a solitary mandibular plasmacytoma in a 53-year-old male Caucasian patient. The histological examination of the specimen was positive for a plasmacytoma with anaplastic appearance. Since the patient refused a demolitive surgical treatment, he was treated with a local radiation therapy of 4000 rads over a 20-day period and polychemotherapy with cyclophosphamide, prednisone and melphalan. Six years after starting radiation treatment the patient is free of recurrent primary disease and not affected by multiple localization. In conclusion, the solitary bone plasmacytoma represents an initial stage of the multiple myeloma rather than a distinct clinical pathology. Unfortunately, the diagnosis of the plasmacytoma is only rarely carried out in the early phases of the disease. The importance of the identification of the initial stage without a clear M component, as in the reported case, is self-evident, since the prognosis is related to the mass of plasmacytoma cells that are present at the time of the diagnosis. The purpose of this study is to report an extremely rare case of solitary bone plasmacytoma with a mandibular localization treated with radio- and polychemotherapy. SN - 0901-5027 UR - https://www.unboundmedicine.com/medline/citation/11829241/Early_clinical_diagnosis_of_solitary_plasmacytoma_of_the_jaws:_a_case_report_with_a_six_year_follow_up_ DB - PRIME DP - Unbound Medicine ER -