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Eremophilane sesquiterpenes from Cacalia ainsliaeflora.
Planta Med. 2002 Jan; 68(1):55-9.PM

Abstract

Chemical investigation of Cacalia ainsliaeflora afforded four new eremophilane sesquiterpenes (1 - 3, 5) and a known sesquiterpene (4), which were identified as 3 beta-angeloyloxy-8 alpha-hydroxy-6 beta-methoxyeremophil-7(11),9(10)-dien-8,12-olide (1), 3 beta-angeloyloxy-6 beta,8 alpha-dihydroxyeremophil-7(11),9(10)-dien-8,12-olide (2), 3 beta-angeloyloxy-8 alpha-hydroxy-6 beta-ethoxyeremophil-7(11),9(10)-dien-8,12-olide (3), 3 beta-angeloyloxy-8-oxo-eremphila-6,9-dien-12-oic acid (4), and 3,8-oxo-eremophila-6,9-dien-12-oic acid (5) respectively. These compounds were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis, and compounds 1, 2, 4 and 5 showed weak antibacterial activity. The structures of the compounds were established by 1D and 2D NMR experiments.

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Authors+Show Affiliations

Mao M
Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, People's Republic of China.
Jia Z
No affiliation info available

MeSH

AsteraceaeBacillus subtilisBacteriaEscherichia coliMedicine, Chinese TraditionalMicrobial Sensitivity TestsNaphthalenesPlant ExtractsPlant RootsPolycyclic SesquiterpenesSesquiterpenesStaphylococcus aureus

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11842328

Citation

Mao, Manjun, and Zhongjian Jia. "Eremophilane Sesquiterpenes From Cacalia Ainsliaeflora." Planta Medica, vol. 68, no. 1, 2002, pp. 55-9.
Mao M, Jia Z. Eremophilane sesquiterpenes from Cacalia ainsliaeflora. Planta Med. 2002;68(1):55-9.
Mao, M., & Jia, Z. (2002). Eremophilane sesquiterpenes from Cacalia ainsliaeflora. Planta Medica, 68(1), 55-9.
Mao M, Jia Z. Eremophilane Sesquiterpenes From Cacalia Ainsliaeflora. Planta Med. 2002;68(1):55-9. PubMed PMID: 11842328.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Eremophilane sesquiterpenes from Cacalia ainsliaeflora. AU - Mao,Manjun, AU - Jia,Zhongjian, PY - 2002/2/14/pubmed PY - 2002/5/9/medline PY - 2002/2/14/entrez SP - 55 EP - 9 JF - Planta medica JO - Planta Med VL - 68 IS - 1 N2 - Chemical investigation of Cacalia ainsliaeflora afforded four new eremophilane sesquiterpenes (1 - 3, 5) and a known sesquiterpene (4), which were identified as 3 beta-angeloyloxy-8 alpha-hydroxy-6 beta-methoxyeremophil-7(11),9(10)-dien-8,12-olide (1), 3 beta-angeloyloxy-6 beta,8 alpha-dihydroxyeremophil-7(11),9(10)-dien-8,12-olide (2), 3 beta-angeloyloxy-8 alpha-hydroxy-6 beta-ethoxyeremophil-7(11),9(10)-dien-8,12-olide (3), 3 beta-angeloyloxy-8-oxo-eremphila-6,9-dien-12-oic acid (4), and 3,8-oxo-eremophila-6,9-dien-12-oic acid (5) respectively. These compounds were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis, and compounds 1, 2, 4 and 5 showed weak antibacterial activity. The structures of the compounds were established by 1D and 2D NMR experiments. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/11842328/Eremophilane_sesquiterpenes_from_Cacalia_ainsliaeflora_ L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2002-19872 DB - PRIME DP - Unbound Medicine ER -