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A cross-sectional study on association of calcium intake with blood pressure in Japanese population.
J Hum Hypertens. 2002 Feb; 16(2):105-10.JH

Abstract

To investigate the association of calcium intake independently of other nutrients already known as predictors of hypertension, a cross-sectional study was carried out on the same population in Japan as used for the INTERSALT study. Dietary calcium intake was estimated from a 1-day 24-h recall. Sodium and potassium intakes were evaluated by 24-h urinary excretion. Data from 476 subjects aged 20-59 years, 230 men and 246 women, were analysed. The mean dietary calcium intake ranged from 557 to 608 mg/day among men, and from 528 to 639 mg/day among women. Among men, the pooled estimate of the regression coefficients of blood pressure (mm Hg) per 100 mg increase of calcium intake, adjusted for age and body mass index (BMI), were -0.42 mm Hg for systolic blood pressure (SBP) and -0.35 mm Hg for diastolic blood pressure (DBP), but there was no statistical significance. Among women, the pooled estimates of regression coefficients adjusted for age and BMI were -0.92 mm Hg for SBP and -0.83 mm Hg for DBP with statistical significance. After adjustment for age, BMI, alcohol intake and urinary excretion of sodium and potassium, the pooled estimate of calcium intake was -0.66 mm Hg for DBP with statistical significance and -0.70 mm Hg for SBP. A significant negative association of calcium intake with blood pressure was observed among the subjects in Osaka. Our study suggests that increased calcium intake may provide a benefit of lowering blood pressure independently of other minerals such as sodium and potassium.

Authors+Show Affiliations

Kanazawa Medical University, Ishikawa, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11850767

Citation

Morikawa, Y, et al. "A Cross-sectional Study On Association of Calcium Intake With Blood Pressure in Japanese Population." Journal of Human Hypertension, vol. 16, no. 2, 2002, pp. 105-10.
Morikawa Y, Nakagawa H, Okayama A, et al. A cross-sectional study on association of calcium intake with blood pressure in Japanese population. J Hum Hypertens. 2002;16(2):105-10.
Morikawa, Y., Nakagawa, H., Okayama, A., Mikawa, K., Sakata, K., Miura, K., Ishizaki, M., Yoshita, K., Naruse, Y., Kagamimori, S., Hashimoto, T., & Ueshima, H. (2002). A cross-sectional study on association of calcium intake with blood pressure in Japanese population. Journal of Human Hypertension, 16(2), 105-10.
Morikawa Y, et al. A Cross-sectional Study On Association of Calcium Intake With Blood Pressure in Japanese Population. J Hum Hypertens. 2002;16(2):105-10. PubMed PMID: 11850767.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A cross-sectional study on association of calcium intake with blood pressure in Japanese population. AU - Morikawa,Y, AU - Nakagawa,H, AU - Okayama,A, AU - Mikawa,K, AU - Sakata,K, AU - Miura,K, AU - Ishizaki,M, AU - Yoshita,K, AU - Naruse,Y, AU - Kagamimori,S, AU - Hashimoto,T, AU - Ueshima,H, PY - 2001/05/25/received PY - 2001/09/06/revised PY - 2001/09/06/accepted PY - 2002/2/19/pubmed PY - 2002/3/21/medline PY - 2002/2/19/entrez SP - 105 EP - 10 JF - Journal of human hypertension JO - J Hum Hypertens VL - 16 IS - 2 N2 - To investigate the association of calcium intake independently of other nutrients already known as predictors of hypertension, a cross-sectional study was carried out on the same population in Japan as used for the INTERSALT study. Dietary calcium intake was estimated from a 1-day 24-h recall. Sodium and potassium intakes were evaluated by 24-h urinary excretion. Data from 476 subjects aged 20-59 years, 230 men and 246 women, were analysed. The mean dietary calcium intake ranged from 557 to 608 mg/day among men, and from 528 to 639 mg/day among women. Among men, the pooled estimate of the regression coefficients of blood pressure (mm Hg) per 100 mg increase of calcium intake, adjusted for age and body mass index (BMI), were -0.42 mm Hg for systolic blood pressure (SBP) and -0.35 mm Hg for diastolic blood pressure (DBP), but there was no statistical significance. Among women, the pooled estimates of regression coefficients adjusted for age and BMI were -0.92 mm Hg for SBP and -0.83 mm Hg for DBP with statistical significance. After adjustment for age, BMI, alcohol intake and urinary excretion of sodium and potassium, the pooled estimate of calcium intake was -0.66 mm Hg for DBP with statistical significance and -0.70 mm Hg for SBP. A significant negative association of calcium intake with blood pressure was observed among the subjects in Osaka. Our study suggests that increased calcium intake may provide a benefit of lowering blood pressure independently of other minerals such as sodium and potassium. SN - 0950-9240 UR - https://www.unboundmedicine.com/medline/citation/11850767/A_cross_sectional_study_on_association_of_calcium_intake_with_blood_pressure_in_Japanese_population_ L2 - https://doi.org/10.1038/sj.jhh.1001314 DB - PRIME DP - Unbound Medicine ER -