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New lupane glycosides from Pulsatilla chinensis.
Planta Med. 2002 Feb; 68(2):183-6.PM

Abstract

Two new lupane glycosides along with five known triterpenoids were isolated from the roots of Pulsatilla chinensis (Ranunculaceae). The structures of the new glycosides were determined to be 3-O-beta-D-glucopyranosyl(1-->3)-alpha-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranosyl ester (pulsatilloside D, 6) and 3-O-[beta-D-glucopyranosyl(1-->4)][alpha-L-rhamnopyranosyl(1-->2)]-alpha-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranosyl ester (pulsatilloside E, 7) by spectroscopic analysis and chemical methods. The compounds were evaluated for cytotoxic activities against K-562 human leukemia and HeLa cells.

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Publisher Full Text

Authors

Ye W
No affiliation info available
Zhang Q
No affiliation info available
Hsiao WW
No affiliation info available
Zhao S
No affiliation info available
Che CT
No affiliation info available

MeSH

Biological AssayCarbohydrate SequenceChinaHeLa CellsHumansK562 CellsMagnetic Resonance SpectroscopyMedicine, Chinese TraditionalMolecular Sequence DataMolecular StructurePlant ExtractsPlant RootsRanunculaceaeSaponinsTriterpenes

Pub Type(s)

Letter
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11859478

Citation

Ye, Wencai, et al. "New Lupane Glycosides From Pulsatilla Chinensis." Planta Medica, vol. 68, no. 2, 2002, pp. 183-6.
Ye W, Zhang Q, Hsiao WW, et al. New lupane glycosides from Pulsatilla chinensis. Planta Med. 2002;68(2):183-6.
Ye, W., Zhang, Q., Hsiao, W. W., Zhao, S., & Che, C. T. (2002). New lupane glycosides from Pulsatilla chinensis. Planta Medica, 68(2), 183-6.
Ye W, et al. New Lupane Glycosides From Pulsatilla Chinensis. Planta Med. 2002;68(2):183-6. PubMed PMID: 11859478.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New lupane glycosides from Pulsatilla chinensis. AU - Ye,Wencai, AU - Zhang,Qingwen, AU - Hsiao,Wendy W, AU - Zhao,Shouxun, AU - Che,Chun-Tao, PY - 2002/2/23/pubmed PY - 2002/5/29/medline PY - 2002/2/23/entrez SP - 183 EP - 6 JF - Planta medica JO - Planta Med VL - 68 IS - 2 N2 - Two new lupane glycosides along with five known triterpenoids were isolated from the roots of Pulsatilla chinensis (Ranunculaceae). The structures of the new glycosides were determined to be 3-O-beta-D-glucopyranosyl(1-->3)-alpha-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranosyl ester (pulsatilloside D, 6) and 3-O-[beta-D-glucopyranosyl(1-->4)][alpha-L-rhamnopyranosyl(1-->2)]-alpha-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranosyl ester (pulsatilloside E, 7) by spectroscopic analysis and chemical methods. The compounds were evaluated for cytotoxic activities against K-562 human leukemia and HeLa cells. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/11859478/New_lupane_glycosides_from_Pulsatilla_chinensis_ L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2002-20254 DB - PRIME DP - Unbound Medicine ER -