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Prospective study of moderate alcohol consumption and risk of hypertension in young women.

Abstract

BACKGROUND

Heavy alcohol consumption is associated with an increased risk of hypertension. However, the effect of moderate alcohol consumption; the specific effects of wine, beer, and liquor; and the pattern of drinking in relation to risk of hypertension among young women are unclear.

METHODS

We prospectively examined the association between alcohol consumption and subsequent risk of hypertension among 70 891 women 25 to 42 years of age.

RESULTS

During the 8 years of follow-up, 4188 cases (5.9%) of incident hypertension were reported. After adjustment for multiple covariates, the association between alcohol consumption and risk of hypertension followed a J-shaped curve. Compared with nondrinkers, the risk of developing hypertension according to average number of drinks consumed per day was as follows: 0.25 or less, 0.96 (95% confidence interval [CI], 0.89-1.03); 0.26 to 0.50, 0.86 (95% CI, 0.75-0.98); 0.51 to 1.00, 0.92 (95% CI, 0.82-1.04); 1.01 to 1.50, 1.00 (95% CI, 0.80-1.24); 1.51 to 2.00, 1.20 (95% CI, 0.92-1.58); and more than 2.0 drinks, 1.31 (95% CI, 1.02-1.68). Exclusion of past drinkers yielded similar results. Among women in the highest category of alcohol consumption, there was a suggestion that the increased risk of hypertension was present regardless of the specific beverage consumed (beer, wine, or liquor). Episodic drinking, defined as consumption of more than 10.5 drinks over 3 or fewer days per week, was not associated with increased risk of hypertension (relative risk, 0.80; 95% CI, 0.51-1.23).

CONCLUSIONS

The association between alcohol consumption and risk of chronic hypertension in young women follows a J-shaped curve, with light drinkers demonstrating a modest decrease in risk and more regular heavy drinkers demonstrating an increase in risk.

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  • Authors+Show Affiliations

    ,

    Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Ave, Boston, MA 02115, USA. rthadhani@partners.org

    , , , ,

    Source

    Archives of internal medicine 162:5 2002 Mar 11 pg 569-74

    MeSH

    Adult
    Alcohol Drinking
    Beer
    Cohort Studies
    Female
    Humans
    Hypertension
    Prospective Studies
    Risk Assessment
    Risk Factors
    Wine

    Pub Type(s)

    Journal Article
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    11871925

    Citation

    Thadhani, Ravi, et al. "Prospective Study of Moderate Alcohol Consumption and Risk of Hypertension in Young Women." Archives of Internal Medicine, vol. 162, no. 5, 2002, pp. 569-74.
    Thadhani R, Camargo CA, Stampfer MJ, et al. Prospective study of moderate alcohol consumption and risk of hypertension in young women. Arch Intern Med. 2002;162(5):569-74.
    Thadhani, R., Camargo, C. A., Stampfer, M. J., Curhan, G. C., Willett, W. C., & Rimm, E. B. (2002). Prospective study of moderate alcohol consumption and risk of hypertension in young women. Archives of Internal Medicine, 162(5), pp. 569-74.
    Thadhani R, et al. Prospective Study of Moderate Alcohol Consumption and Risk of Hypertension in Young Women. Arch Intern Med. 2002 Mar 11;162(5):569-74. PubMed PMID: 11871925.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Prospective study of moderate alcohol consumption and risk of hypertension in young women. AU - Thadhani,Ravi, AU - Camargo,Carlos A,Jr AU - Stampfer,Meir J, AU - Curhan,Gary C, AU - Willett,Walter C, AU - Rimm,Eric B, PY - 2002/3/5/pubmed PY - 2002/3/23/medline PY - 2002/3/5/entrez SP - 569 EP - 74 JF - Archives of internal medicine JO - Arch. Intern. Med. VL - 162 IS - 5 N2 - BACKGROUND: Heavy alcohol consumption is associated with an increased risk of hypertension. However, the effect of moderate alcohol consumption; the specific effects of wine, beer, and liquor; and the pattern of drinking in relation to risk of hypertension among young women are unclear. METHODS: We prospectively examined the association between alcohol consumption and subsequent risk of hypertension among 70 891 women 25 to 42 years of age. RESULTS: During the 8 years of follow-up, 4188 cases (5.9%) of incident hypertension were reported. After adjustment for multiple covariates, the association between alcohol consumption and risk of hypertension followed a J-shaped curve. Compared with nondrinkers, the risk of developing hypertension according to average number of drinks consumed per day was as follows: 0.25 or less, 0.96 (95% confidence interval [CI], 0.89-1.03); 0.26 to 0.50, 0.86 (95% CI, 0.75-0.98); 0.51 to 1.00, 0.92 (95% CI, 0.82-1.04); 1.01 to 1.50, 1.00 (95% CI, 0.80-1.24); 1.51 to 2.00, 1.20 (95% CI, 0.92-1.58); and more than 2.0 drinks, 1.31 (95% CI, 1.02-1.68). Exclusion of past drinkers yielded similar results. Among women in the highest category of alcohol consumption, there was a suggestion that the increased risk of hypertension was present regardless of the specific beverage consumed (beer, wine, or liquor). Episodic drinking, defined as consumption of more than 10.5 drinks over 3 or fewer days per week, was not associated with increased risk of hypertension (relative risk, 0.80; 95% CI, 0.51-1.23). CONCLUSIONS: The association between alcohol consumption and risk of chronic hypertension in young women follows a J-shaped curve, with light drinkers demonstrating a modest decrease in risk and more regular heavy drinkers demonstrating an increase in risk. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/11871925/Prospective_study_of_moderate_alcohol_consumption_and_risk_of_hypertension_in_young_women_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/162/pg/569 DB - PRIME DP - Unbound Medicine ER -