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Soy, soy phytoestrogens and cardiovascular disease.
J Nutr 2002; 132(3):566S-569SJN

Abstract

Dietary soy protein has been shown to have several beneficial effects on cardiovascular health. The best-documented effect is on plasma lipid and lipoprotein concentrations, with reductions of approximately 10% in LDL cholesterol concentrations (somewhat greater for individuals with high pretreatment LDL cholesterol concentrations) and small increases in HDL cholesterol concentrations. Dietary soy protein improves flow-mediated arterial dilation of postmenopausal women but worsens that of men. Soy isoflavone extracts improve systemic arterial compliance, an indicator of atherosclerosis extent. Complete soy protein but not alcohol-washed soy protein reduces atherosclerosis of postmenopausal monkeys. No definite experimental evidence exists currently to establish that the cardiovascular benefits of soy protein are accounted for by its isoflavones.

Authors+Show Affiliations

Comparative Medicine Clinical Research Center, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. tclarkso@wfubmc.edu

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

11880594

Citation

Clarkson, Thomas B.. "Soy, Soy Phytoestrogens and Cardiovascular Disease." The Journal of Nutrition, vol. 132, no. 3, 2002, 566S-569S.
Clarkson TB. Soy, soy phytoestrogens and cardiovascular disease. J Nutr. 2002;132(3):566S-569S.
Clarkson, T. B. (2002). Soy, soy phytoestrogens and cardiovascular disease. The Journal of Nutrition, 132(3), 566S-569S.
Clarkson TB. Soy, Soy Phytoestrogens and Cardiovascular Disease. J Nutr. 2002;132(3):566S-569S. PubMed PMID: 11880594.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Soy, soy phytoestrogens and cardiovascular disease. A1 - Clarkson,Thomas B, PY - 2002/3/7/pubmed PY - 2002/4/10/medline PY - 2002/3/7/entrez SP - 566S EP - 569S JF - The Journal of nutrition JO - J. Nutr. VL - 132 IS - 3 N2 - Dietary soy protein has been shown to have several beneficial effects on cardiovascular health. The best-documented effect is on plasma lipid and lipoprotein concentrations, with reductions of approximately 10% in LDL cholesterol concentrations (somewhat greater for individuals with high pretreatment LDL cholesterol concentrations) and small increases in HDL cholesterol concentrations. Dietary soy protein improves flow-mediated arterial dilation of postmenopausal women but worsens that of men. Soy isoflavone extracts improve systemic arterial compliance, an indicator of atherosclerosis extent. Complete soy protein but not alcohol-washed soy protein reduces atherosclerosis of postmenopausal monkeys. No definite experimental evidence exists currently to establish that the cardiovascular benefits of soy protein are accounted for by its isoflavones. SN - 0022-3166 UR - https://www.unboundmedicine.com/medline/citation/11880594/Soy_soy_phytoestrogens_and_cardiovascular_disease_ L2 - https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/132.3.566S DB - PRIME DP - Unbound Medicine ER -