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Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria.
J Ethnopharmacol 2002; 80(1):1-7JE

Abstract

Propolis collected from a cerrado area in Minas Gerais State, Brazil, was subjected to chromatography on silica gel column and to partition between immiscible solvents. Propolis aqueous-ethanolic extract and fractions obtained were tested for inhibitory activity against periodontitis-causing bacteria. All of the assayed bacterium species were susceptible to propolis extract. The two fractionation methodologies yielded fractions which were active against bacteria, with minimum inhibitory concentrations (MIC) ranging from 64 to 1024 microg/ml. TLC and HPLC analyses of the extract and of active fractions showed the presence of phenolic compounds of varied polarity. None of the assayed fractions was more active than the extract, suggesting that the antibacterial activity is probably due to the synergistic effect of several compounds.

Authors+Show Affiliations

Departamento de Microbiologia, Laboratório de Biologia de Microrganismos, Instituto de Ciências Biológicas da Universidade Federal de Minas Gerais, Caixa Postal 486, Avenida Antônio Carlos 6627, CEP 31270 901, MG, Belo Horizonte, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11891080

Citation

Santos, F A., et al. "Antibacterial Activity of Brazilian Propolis and Fractions Against Oral Anaerobic Bacteria." Journal of Ethnopharmacology, vol. 80, no. 1, 2002, pp. 1-7.
Santos FA, Bastos EM, Uzeda M, et al. Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria. J Ethnopharmacol. 2002;80(1):1-7.
Santos, F. A., Bastos, E. M., Uzeda, M., Carvalho, M. A., Farias, L. M., Moreira, E. S., & Braga, F. C. (2002). Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria. Journal of Ethnopharmacology, 80(1), pp. 1-7.
Santos FA, et al. Antibacterial Activity of Brazilian Propolis and Fractions Against Oral Anaerobic Bacteria. J Ethnopharmacol. 2002;80(1):1-7. PubMed PMID: 11891080.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria. AU - Santos,F A, AU - Bastos,E M A, AU - Uzeda,M, AU - Carvalho,M A R, AU - Farias,L M, AU - Moreira,E S A, AU - Braga,F C, PY - 2002/3/14/pubmed PY - 2002/9/21/medline PY - 2002/3/14/entrez SP - 1 EP - 7 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 80 IS - 1 N2 - Propolis collected from a cerrado area in Minas Gerais State, Brazil, was subjected to chromatography on silica gel column and to partition between immiscible solvents. Propolis aqueous-ethanolic extract and fractions obtained were tested for inhibitory activity against periodontitis-causing bacteria. All of the assayed bacterium species were susceptible to propolis extract. The two fractionation methodologies yielded fractions which were active against bacteria, with minimum inhibitory concentrations (MIC) ranging from 64 to 1024 microg/ml. TLC and HPLC analyses of the extract and of active fractions showed the presence of phenolic compounds of varied polarity. None of the assayed fractions was more active than the extract, suggesting that the antibacterial activity is probably due to the synergistic effect of several compounds. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/11891080/Antibacterial_activity_of_Brazilian_propolis_and_fractions_against_oral_anaerobic_bacteria_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S037887410200003X DB - PRIME DP - Unbound Medicine ER -