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Pathologic features of superficial esophageal squamous cell carcinoma with lymph node and distal metastasis.
Cancer. 2002 Jan 15; 94(2):570-5.C

Abstract

BACKGROUND

Endoscopic mucosal resection (EMR) is a less invasive localized treatment for patients with esophageal carcinoma. However, indications for EMR use in cases of superficial esophageal carcinoma are controversial. The authors evaluated histopathologic risk factors for lymph node metastasis and recurrence.

METHODS

In the specimens resected, the authors examined depth, the superficial area and the area attached to or infiltrating the lamina muscularis mucosa.

RESULTS

The authors found that the superficial area and the attached or infiltrated area reflected the depth of the tumor. However, there was a recurrence of esophageal carcinoma even in m3 cases attached only to the lamina muscularis mucosa.

CONCLUSIONS

The authors concluded that ml and m2 esophageal carcinoma had almost no risk of lymph node metastasis and recurrence no matter how extensive the superficial area. In addition, sm2 and sm3 carcinoma have a high frequency of lymph node metastasis and recurrence. M3 and sm1 carcinoma run the risk of lymph node metastasis and recurrence however small the superficial area and the area attached to or infiltrating the lamina muscularis mucosa. Treatment strategies for patients with superficial esophageal carcinoma, including EMR, should take the above findings into account.

Authors+Show Affiliations

Department of Surgery and Science, Faculty of Medicine, Kyushu University, Fukuoka, Japan. ayushi@mint.ocn.ne.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11900242

Citation

Araki, Koshi, et al. "Pathologic Features of Superficial Esophageal Squamous Cell Carcinoma With Lymph Node and Distal Metastasis." Cancer, vol. 94, no. 2, 2002, pp. 570-5.
Araki K, Ohno S, Egashira A, et al. Pathologic features of superficial esophageal squamous cell carcinoma with lymph node and distal metastasis. Cancer. 2002;94(2):570-5.
Araki, K., Ohno, S., Egashira, A., Saeki, H., Kawaguchi, H., & Sugimachi, K. (2002). Pathologic features of superficial esophageal squamous cell carcinoma with lymph node and distal metastasis. Cancer, 94(2), 570-5.
Araki K, et al. Pathologic Features of Superficial Esophageal Squamous Cell Carcinoma With Lymph Node and Distal Metastasis. Cancer. 2002 Jan 15;94(2):570-5. PubMed PMID: 11900242.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pathologic features of superficial esophageal squamous cell carcinoma with lymph node and distal metastasis. AU - Araki,Koshi, AU - Ohno,Shinji, AU - Egashira,Akinori, AU - Saeki,Hiroshi, AU - Kawaguchi,Hidetoshi, AU - Sugimachi,Keizo, PY - 2002/3/20/pubmed PY - 2002/4/18/medline PY - 2002/3/20/entrez SP - 570 EP - 5 JF - Cancer JO - Cancer VL - 94 IS - 2 N2 - BACKGROUND: Endoscopic mucosal resection (EMR) is a less invasive localized treatment for patients with esophageal carcinoma. However, indications for EMR use in cases of superficial esophageal carcinoma are controversial. The authors evaluated histopathologic risk factors for lymph node metastasis and recurrence. METHODS: In the specimens resected, the authors examined depth, the superficial area and the area attached to or infiltrating the lamina muscularis mucosa. RESULTS: The authors found that the superficial area and the attached or infiltrated area reflected the depth of the tumor. However, there was a recurrence of esophageal carcinoma even in m3 cases attached only to the lamina muscularis mucosa. CONCLUSIONS: The authors concluded that ml and m2 esophageal carcinoma had almost no risk of lymph node metastasis and recurrence no matter how extensive the superficial area. In addition, sm2 and sm3 carcinoma have a high frequency of lymph node metastasis and recurrence. M3 and sm1 carcinoma run the risk of lymph node metastasis and recurrence however small the superficial area and the area attached to or infiltrating the lamina muscularis mucosa. Treatment strategies for patients with superficial esophageal carcinoma, including EMR, should take the above findings into account. SN - 0008-543X UR - https://www.unboundmedicine.com/medline/citation/11900242/Pathologic_features_of_superficial_esophageal_squamous_cell_carcinoma_with_lymph_node_and_distal_metastasis_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0008-543X&date=2002&volume=94&issue=2&spage=570 DB - PRIME DP - Unbound Medicine ER -