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Utility of the WHO neurobehavioral core test battery in Chinese workers-a meta-analysis.
Environ Res. 2002 Feb; 88(2):94-102.ER

Abstract

We performed a meta-analysis to determine the most sensitive subtests of the WHO Neurobehavioral Core Test Battery (NCTB) when administered to Chinese workers. Extensive Chinese Biological Medical Database and MEDLINE searches, review of cited references, and discussion with other investigators were undertaken. Data were extracted from 39 eligible studies; the summary effects (effect sizes) were calculated using a fixed-effect model. Various exposure agents showed different sensitivities to the seven subtests of NCTB. For mercury-exposure, the Benton Visual Retention was the most sensitive subtest, with an effect size (95% CI) of 6.0 (4.4-7.6). For lead-exposure, the most sensitive subtests were the Pursuit Aiming II and Profile of Mood States, with effect sizes (95% CI) of 11.3 (8.3-14.3) and 10.6 (7.5-13.7), respectively. For organic solvents-exposure, Digit Span, Pursuit Aiming II, and Digit Symbol were the most sensitive subtests, with effect sizes (95- CI) of 4.7 (3.3-6.1), 4.6 (3.1-6.1), and 4.1 (2.7-5.5), respectively.

Authors+Show Affiliations

Department of Environmental Health, Harvard School of Public Health, Occupational Health Program, 665 Huntington Avenue, Boston, Massachusetts, 02115, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11908934

Citation

Zhou, Wei, et al. "Utility of the WHO Neurobehavioral Core Test Battery in Chinese Workers-a Meta-analysis." Environmental Research, vol. 88, no. 2, 2002, pp. 94-102.
Zhou W, Liang Y, Christiani DC. Utility of the WHO neurobehavioral core test battery in Chinese workers-a meta-analysis. Environ Res. 2002;88(2):94-102.
Zhou, W., Liang, Y., & Christiani, D. C. (2002). Utility of the WHO neurobehavioral core test battery in Chinese workers-a meta-analysis. Environmental Research, 88(2), 94-102.
Zhou W, Liang Y, Christiani DC. Utility of the WHO Neurobehavioral Core Test Battery in Chinese Workers-a Meta-analysis. Environ Res. 2002;88(2):94-102. PubMed PMID: 11908934.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Utility of the WHO neurobehavioral core test battery in Chinese workers-a meta-analysis. AU - Zhou,Wei, AU - Liang,Youxin, AU - Christiani,David C, PY - 2002/3/23/pubmed PY - 2002/5/1/medline PY - 2002/3/23/entrez SP - 94 EP - 102 JF - Environmental research JO - Environ Res VL - 88 IS - 2 N2 - We performed a meta-analysis to determine the most sensitive subtests of the WHO Neurobehavioral Core Test Battery (NCTB) when administered to Chinese workers. Extensive Chinese Biological Medical Database and MEDLINE searches, review of cited references, and discussion with other investigators were undertaken. Data were extracted from 39 eligible studies; the summary effects (effect sizes) were calculated using a fixed-effect model. Various exposure agents showed different sensitivities to the seven subtests of NCTB. For mercury-exposure, the Benton Visual Retention was the most sensitive subtest, with an effect size (95% CI) of 6.0 (4.4-7.6). For lead-exposure, the most sensitive subtests were the Pursuit Aiming II and Profile of Mood States, with effect sizes (95% CI) of 11.3 (8.3-14.3) and 10.6 (7.5-13.7), respectively. For organic solvents-exposure, Digit Span, Pursuit Aiming II, and Digit Symbol were the most sensitive subtests, with effect sizes (95- CI) of 4.7 (3.3-6.1), 4.6 (3.1-6.1), and 4.1 (2.7-5.5), respectively. SN - 0013-9351 UR - https://www.unboundmedicine.com/medline/citation/11908934/Utility_of_the_WHO_neurobehavioral_core_test_battery_in_Chinese_workers_a_meta_analysis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0013935101943221 DB - PRIME DP - Unbound Medicine ER -