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The n-3 and n-6 polyunsaturated fatty acid composition of plasma phospholipids in pregnant women and their infants. relationship with maternal linoleic acid intake.
Clin Chem Lab Med 2002; 40(1):32-9CC

Abstract

The availability of long-chain polyunsaturated fatty acids during infancy has been related to neonatal growth and development. Fatty acid concentration at birth is an important predictor of postnatal level. The primary aim of this study was to provide a description of the distribution of n-3 and n-6 polyunsaturated fatty acids in the plasma phospholipid fraction of pregnant women remaining on a Western-style diet and their neonates. The plasma phospholipid polyunsaturated fatty acid composition was determined by gas-liquid chromatography in 889 mother-infant pairs. Blood samples were taken during the first, second and third trimester of pregnancy, at delivery, and from the umbilical vein at birth. Mean (+/- SD) fatty acid concentrations are reported in mg/l and as percentage of total fatty acids (% wt/wt). In addition, the 10th, 25th, 50th, 75th and 90th percentiles are given. The distribution of docosahexaenoic acid (22:6n-3) and arachidonic acid (20:4n-6) concentrations in umbilical plasma phospholipids is also reported as a function of gestational age and maternal linoleic acid intake during pregnancy. This data can be be used as a reference for future studies and may aid in identifying term infants with a relatively low long-chain polyene status at birth.

Authors+Show Affiliations

Nutrition and Toxicology Research Institute Maastricht, University of Maastricht, The Netherlands. p.rump@medgen.azg.nlNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11916268

Citation

Rum, Patrick, and Gerard Hornstra. "The N-3 and N-6 Polyunsaturated Fatty Acid Composition of Plasma Phospholipids in Pregnant Women and Their Infants. Relationship With Maternal Linoleic Acid Intake." Clinical Chemistry and Laboratory Medicine, vol. 40, no. 1, 2002, pp. 32-9.
Rum P, Hornstra G. The n-3 and n-6 polyunsaturated fatty acid composition of plasma phospholipids in pregnant women and their infants. relationship with maternal linoleic acid intake. Clin Chem Lab Med. 2002;40(1):32-9.
Rum, P., & Hornstra, G. (2002). The n-3 and n-6 polyunsaturated fatty acid composition of plasma phospholipids in pregnant women and their infants. relationship with maternal linoleic acid intake. Clinical Chemistry and Laboratory Medicine, 40(1), pp. 32-9.
Rum P, Hornstra G. The N-3 and N-6 Polyunsaturated Fatty Acid Composition of Plasma Phospholipids in Pregnant Women and Their Infants. Relationship With Maternal Linoleic Acid Intake. Clin Chem Lab Med. 2002;40(1):32-9. PubMed PMID: 11916268.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The n-3 and n-6 polyunsaturated fatty acid composition of plasma phospholipids in pregnant women and their infants. relationship with maternal linoleic acid intake. AU - Rum,Patrick, AU - Hornstra,Gerard, PY - 2002/3/28/pubmed PY - 2002/9/28/medline PY - 2002/3/28/entrez SP - 32 EP - 9 JF - Clinical chemistry and laboratory medicine JO - Clin. Chem. Lab. Med. VL - 40 IS - 1 N2 - The availability of long-chain polyunsaturated fatty acids during infancy has been related to neonatal growth and development. Fatty acid concentration at birth is an important predictor of postnatal level. The primary aim of this study was to provide a description of the distribution of n-3 and n-6 polyunsaturated fatty acids in the plasma phospholipid fraction of pregnant women remaining on a Western-style diet and their neonates. The plasma phospholipid polyunsaturated fatty acid composition was determined by gas-liquid chromatography in 889 mother-infant pairs. Blood samples were taken during the first, second and third trimester of pregnancy, at delivery, and from the umbilical vein at birth. Mean (+/- SD) fatty acid concentrations are reported in mg/l and as percentage of total fatty acids (% wt/wt). In addition, the 10th, 25th, 50th, 75th and 90th percentiles are given. The distribution of docosahexaenoic acid (22:6n-3) and arachidonic acid (20:4n-6) concentrations in umbilical plasma phospholipids is also reported as a function of gestational age and maternal linoleic acid intake during pregnancy. This data can be be used as a reference for future studies and may aid in identifying term infants with a relatively low long-chain polyene status at birth. SN - 1434-6621 UR - https://www.unboundmedicine.com/medline/citation/11916268/The_n_3_and_n_6_polyunsaturated_fatty_acid_composition_of_plasma_phospholipids_in_pregnant_women_and_their_infants__relationship_with_maternal_linoleic_acid_intake_ L2 - https://www.degruyter.com/doi/10.1515/CCLM.2002.007 DB - PRIME DP - Unbound Medicine ER -