Tags

Type your tag names separated by a space and hit enter

Maternal history, sensitization to allergens, and current wheezing, rhinitis, and eczema among children in Costa Rica.
Pediatr Pulmonol. 2002 Apr; 33(4):237-43.PP

Abstract

Little is known about the factors associated with asthma, allergic rhinitis, and eczema in Latin American countries. We investigated the relation between potential risk factors and current wheezing, allergic rhinitis, and eczema among 208 Costa Rican children aged 10-13 years participating in phase II of the International Study of Asthma and Allergies in Childhood (ISAAC). The geometric mean (+/- SD) serum total IgE level of children with current wheezing was significantly higher than that of children without current wheezing (533.8 +/- 5.2 vs. 144.7 +/- 6.0 IU/mL, P < 0.01). In a multivariate analysis, a maternal history of asthma, skin test reactivity (STR) to house dust mites, and STR to Alternaria were significantly associated with current wheezing. Children who had a maternal history of asthma had 2.4 times higher odds of current wheezing than those without maternal history of asthma (95% CI for OR = 1.1-5.3). Sensitization to either house dust mite or Alternaria was associated with 3.3 times increased odds of current wheezing (95% CI for OR for STR to dust mite = 1.6-6.7; 95% CI for OR for STR to Alternaria = 1.1-11.0). In a multivariate analysis, STR to house dust mite and STR to cat dander were significantly associated with allergic rhinitis, and a maternal history of eczema and STR to dog dander were associated with eczema in the child. The interaction between familial factors and lifestyle changes resulting from social reforms implemented 60 years ago may explain the high prevalence of atopic diseases in Costa Rica.

Links

Publisher Full Text

Authors+Show Affiliations

Soto-Quiros ME
Department of Pediatrics, Hospital Nacional de Niños, San José, Costa Rica.
Silverman EK
No affiliation info available
Hanson LA
No affiliation info available
Weiss ST
No affiliation info available
Celedón JC
No affiliation info available

MeSH

AdolescentAllergensAlternariaAnimalsAsthmaChildCockroachesCosta RicaEczemaFemaleHumansImmunoglobulin EMaleMitesMultivariate AnalysisPollenPrevalenceRespiratory SoundsRhinitisRisk FactorsSkin Tests

Pub Type(s)

Clinical Trial
Clinical Trial, Phase II
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11921451

Citation

Soto-Quiros, Manuel E., et al. "Maternal History, Sensitization to Allergens, and Current Wheezing, Rhinitis, and Eczema Among Children in Costa Rica." Pediatric Pulmonology, vol. 33, no. 4, 2002, pp. 237-43.
Soto-Quiros ME, Silverman EK, Hanson LA, et al. Maternal history, sensitization to allergens, and current wheezing, rhinitis, and eczema among children in Costa Rica. Pediatr Pulmonol. 2002;33(4):237-43.
Soto-Quiros, M. E., Silverman, E. K., Hanson, L. A., Weiss, S. T., & Celedón, J. C. (2002). Maternal history, sensitization to allergens, and current wheezing, rhinitis, and eczema among children in Costa Rica. Pediatric Pulmonology, 33(4), 237-43.
Soto-Quiros ME, et al. Maternal History, Sensitization to Allergens, and Current Wheezing, Rhinitis, and Eczema Among Children in Costa Rica. Pediatr Pulmonol. 2002;33(4):237-43. PubMed PMID: 11921451.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Maternal history, sensitization to allergens, and current wheezing, rhinitis, and eczema among children in Costa Rica. AU - Soto-Quiros,Manuel E, AU - Silverman,Edwin K, AU - Hanson,Lars A, AU - Weiss,Scott T, AU - Celedón,Juan C, PY - 2002/3/29/pubmed PY - 2002/4/27/medline PY - 2002/3/29/entrez SP - 237 EP - 43 JF - Pediatric pulmonology JO - Pediatr Pulmonol VL - 33 IS - 4 N2 - Little is known about the factors associated with asthma, allergic rhinitis, and eczema in Latin American countries. We investigated the relation between potential risk factors and current wheezing, allergic rhinitis, and eczema among 208 Costa Rican children aged 10-13 years participating in phase II of the International Study of Asthma and Allergies in Childhood (ISAAC). The geometric mean (+/- SD) serum total IgE level of children with current wheezing was significantly higher than that of children without current wheezing (533.8 +/- 5.2 vs. 144.7 +/- 6.0 IU/mL, P < 0.01). In a multivariate analysis, a maternal history of asthma, skin test reactivity (STR) to house dust mites, and STR to Alternaria were significantly associated with current wheezing. Children who had a maternal history of asthma had 2.4 times higher odds of current wheezing than those without maternal history of asthma (95% CI for OR = 1.1-5.3). Sensitization to either house dust mite or Alternaria was associated with 3.3 times increased odds of current wheezing (95% CI for OR for STR to dust mite = 1.6-6.7; 95% CI for OR for STR to Alternaria = 1.1-11.0). In a multivariate analysis, STR to house dust mite and STR to cat dander were significantly associated with allergic rhinitis, and a maternal history of eczema and STR to dog dander were associated with eczema in the child. The interaction between familial factors and lifestyle changes resulting from social reforms implemented 60 years ago may explain the high prevalence of atopic diseases in Costa Rica. SN - 8755-6863 UR - https://www.unboundmedicine.com/medline/citation/11921451/Maternal_history_sensitization_to_allergens_and_current_wheezing_rhinitis_and_eczema_among_children_in_Costa_Rica_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&amp;sid=nlm:pubmed&amp;issn=8755-6863&amp;date=2002&amp;volume=33&amp;issue=4&amp;spage=237 DB - PRIME DP - Unbound Medicine ER -