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Obsessive-compulsive and panic symptoms in patients with first-admission psychosis.
Am J Psychiatry 2002; 159(4):592-8AJ

Abstract

OBJECTIVE

The occurrence, persistence and specificity of the association between comorbid obsessive-compulsive and panic symptoms and three psychotic disorders--schizophrenia/schizoaffective disorder, bipolar disorder with psychosis, and major depression with psychosis--were examined in a first-admission, epidemiologically defined group of patients with psychotic symptoms.

METHOD

The Structured Clinical Interview for DSM-III-R obsessive-compulsive and panic modules were administered at baseline and 24-month follow-up to patients with schizophrenia/schizoaffective disorder (N=225), bipolar disorder with psychosis (N=138), and major depression with psychosis (N=87) participating in the Suffolk County (N.Y.) Mental Health Project. The rates of subsyndromal symptoms and disorder criteria met were compared across the three psychosis groups. Recognition and treatment of anxiety symptoms at initial discharge and impact of the baseline presence of anxiety symptoms on 24-month clinical status were also examined.

RESULTS

Obsessive-compulsive and panic symptoms were present at baseline in 10%-20% of all three groups. There was no specific association between obsessive-compulsive symptoms and any specific psychosis diagnosis; however, women with major depression with psychosis had a significantly higher rate of panic symptoms than the other two groups, and schizophrenia/schizoaffective disorder patients with baseline panic symptoms were significantly more likely to exhibit positive symptoms of psychosis after 24 months.

CONCLUSIONS

The authors found no specific association between obsessive-compulsive symptoms and diagnosis early in the illness course, but the finding of an association between panic symptoms and psychotic depression among female patients and between baseline panic and positive psychotic symptoms in schizophrenia/schizoaffective disorder patients at 24 months suggests the need for further study.

Authors+Show Affiliations

VA Office of Quality and Performance, Washington, DC, USA. thomas.craig@mail.va.govNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

11925297

Citation

Craig, Thomas, et al. "Obsessive-compulsive and Panic Symptoms in Patients With First-admission Psychosis." The American Journal of Psychiatry, vol. 159, no. 4, 2002, pp. 592-8.
Craig T, Hwang MY, Bromet EJ. Obsessive-compulsive and panic symptoms in patients with first-admission psychosis. Am J Psychiatry. 2002;159(4):592-8.
Craig, T., Hwang, M. Y., & Bromet, E. J. (2002). Obsessive-compulsive and panic symptoms in patients with first-admission psychosis. The American Journal of Psychiatry, 159(4), pp. 592-8.
Craig T, Hwang MY, Bromet EJ. Obsessive-compulsive and Panic Symptoms in Patients With First-admission Psychosis. Am J Psychiatry. 2002;159(4):592-8. PubMed PMID: 11925297.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Obsessive-compulsive and panic symptoms in patients with first-admission psychosis. AU - Craig,Thomas, AU - Hwang,Michael Y, AU - Bromet,Evelyn J, PY - 2002/4/2/pubmed PY - 2002/4/19/medline PY - 2002/4/2/entrez SP - 592 EP - 8 JF - The American journal of psychiatry JO - Am J Psychiatry VL - 159 IS - 4 N2 - OBJECTIVE: The occurrence, persistence and specificity of the association between comorbid obsessive-compulsive and panic symptoms and three psychotic disorders--schizophrenia/schizoaffective disorder, bipolar disorder with psychosis, and major depression with psychosis--were examined in a first-admission, epidemiologically defined group of patients with psychotic symptoms. METHOD: The Structured Clinical Interview for DSM-III-R obsessive-compulsive and panic modules were administered at baseline and 24-month follow-up to patients with schizophrenia/schizoaffective disorder (N=225), bipolar disorder with psychosis (N=138), and major depression with psychosis (N=87) participating in the Suffolk County (N.Y.) Mental Health Project. The rates of subsyndromal symptoms and disorder criteria met were compared across the three psychosis groups. Recognition and treatment of anxiety symptoms at initial discharge and impact of the baseline presence of anxiety symptoms on 24-month clinical status were also examined. RESULTS: Obsessive-compulsive and panic symptoms were present at baseline in 10%-20% of all three groups. There was no specific association between obsessive-compulsive symptoms and any specific psychosis diagnosis; however, women with major depression with psychosis had a significantly higher rate of panic symptoms than the other two groups, and schizophrenia/schizoaffective disorder patients with baseline panic symptoms were significantly more likely to exhibit positive symptoms of psychosis after 24 months. CONCLUSIONS: The authors found no specific association between obsessive-compulsive symptoms and diagnosis early in the illness course, but the finding of an association between panic symptoms and psychotic depression among female patients and between baseline panic and positive psychotic symptoms in schizophrenia/schizoaffective disorder patients at 24 months suggests the need for further study. SN - 0002-953X UR - https://www.unboundmedicine.com/medline/citation/11925297/Obsessive_compulsive_and_panic_symptoms_in_patients_with_first_admission_psychosis_ L2 - https://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.159.4.592?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -