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[Intradermal tests with vasomotor agents in chronic noninfectious rhinitis].
Vojnosanit Pregl. 2002 Jan-Feb; 59(1):37-41.VP

Abstract

The aim of this prospective study was to examine the skin reactivity to four vasomotor agents in chronic, non-infectious rhinitis patients, and to determine whether non-allergic rhinitis (NAR) patients differ from allergic rhinitis (AR) patients. Seventy four patients with NAR and 44 with AR were subjected to intradermal testing with papaverine (5 mg/ml), metacholine (0.02, 0.2 and 2.0 mg/ml), histamine (0.01, 0.1, 1.0 and 10.0 micrograms/ml), compound 48/80 (0.01, 0.1, 1.0 and 10.0 micrograms/ml) and saline. It was found that the frequency of pathological skin reactivity to papaverine in the patients with NAR (25/74) was significantly greater (p = 5.0 x 10(-3)) then in the patients with AR (4/44). No significant inter-group difference in skin reactivity to metacholine, histamine, compound 48/80 and saline was observed. The frequency of the total pathological skin reactivity to vasomotor agents, singly and in combinations, in patients with NAR (80%) was significantly greater (p = 0.03) than in patients with AR (61%). These findings suggested that the pathological skin reactivity to papaverine, metacholine, histamine and compound 48/80 was a feature of chronic, non-infectious rhinitis patients and it was more frequently associated with non-allergic than with the allergic etiology of rhinitis.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

srp

PubMed ID

11928189

Citation

Milosević, Dusanka N., et al. "[Intradermal Tests With Vasomotor Agents in Chronic Noninfectious Rhinitis]." Vojnosanitetski Pregled, vol. 59, no. 1, 2002, pp. 37-41.
Milosević DN, Janosević LB, Janosević SB. [Intradermal tests with vasomotor agents in chronic noninfectious rhinitis]. Vojnosanit Pregl. 2002;59(1):37-41.
Milosević, D. N., Janosević, L. B., & Janosević, S. B. (2002). [Intradermal tests with vasomotor agents in chronic noninfectious rhinitis]. Vojnosanitetski Pregled, 59(1), 37-41.
Milosević DN, Janosević LB, Janosević SB. [Intradermal Tests With Vasomotor Agents in Chronic Noninfectious Rhinitis]. Vojnosanit Pregl. 2002 Jan-Feb;59(1):37-41. PubMed PMID: 11928189.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Intradermal tests with vasomotor agents in chronic noninfectious rhinitis]. AU - Milosević,Dusanka N, AU - Janosević,Ljiljana B, AU - Janosević,Slobodanka B, PY - 2002/4/4/pubmed PY - 2002/4/26/medline PY - 2002/4/4/entrez SP - 37 EP - 41 JF - Vojnosanitetski pregled JO - Vojnosanit Pregl VL - 59 IS - 1 N2 - The aim of this prospective study was to examine the skin reactivity to four vasomotor agents in chronic, non-infectious rhinitis patients, and to determine whether non-allergic rhinitis (NAR) patients differ from allergic rhinitis (AR) patients. Seventy four patients with NAR and 44 with AR were subjected to intradermal testing with papaverine (5 mg/ml), metacholine (0.02, 0.2 and 2.0 mg/ml), histamine (0.01, 0.1, 1.0 and 10.0 micrograms/ml), compound 48/80 (0.01, 0.1, 1.0 and 10.0 micrograms/ml) and saline. It was found that the frequency of pathological skin reactivity to papaverine in the patients with NAR (25/74) was significantly greater (p = 5.0 x 10(-3)) then in the patients with AR (4/44). No significant inter-group difference in skin reactivity to metacholine, histamine, compound 48/80 and saline was observed. The frequency of the total pathological skin reactivity to vasomotor agents, singly and in combinations, in patients with NAR (80%) was significantly greater (p = 0.03) than in patients with AR (61%). These findings suggested that the pathological skin reactivity to papaverine, metacholine, histamine and compound 48/80 was a feature of chronic, non-infectious rhinitis patients and it was more frequently associated with non-allergic than with the allergic etiology of rhinitis. SN - 0042-8450 UR - https://www.unboundmedicine.com/medline/citation/11928189/[Intradermal_tests_with_vasomotor_agents_in_chronic_noninfectious_rhinitis]_ L2 - https://medlineplus.gov/hayfever.html DB - PRIME DP - Unbound Medicine ER -