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[Osteoporosis - Evidence based therapy].
Z Gastroenterol 2002; 40 Suppl 1:S57-S61ZG

Abstract

Osteoporosis therapy has been controversially discussed in the past. In the meantime, several therapeutic options to prevent fractures are available for this disease. With respect to proven fracture benefit, however, the quality of evidence from randomised and controlled clinical trials varies substantially among therapies. From systematic research the best external evidence is available for a supplementation with calcium and vitamin D and a therapy with the bisphosphonates alendronate or risedronate, as well as the SERM raloxifene. For other therapeutic agents like fluorides, vitamin D metabolites, calcitonin and etidronate the quality of evidence is much lower. So far, there is no evidence for other pharmaceutical therapies. Hip protectors are effective in the prevention of hip fractures.

Authors+Show Affiliations

Institut für Klinische Osteologie "Gustav Pommer" und Klinik "Der Fürstenhof", Bad Pyrmont, Germany. iko_pyrmont@t-online.deNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

11930292

Citation

Minne, H W., et al. "[Osteoporosis - Evidence Based Therapy]." Zeitschrift Fur Gastroenterologie, vol. 40 Suppl 1, 2002, pp. S57-S61.
Minne HW, Begerow B, Pfeifer M. [Osteoporosis - Evidence based therapy]. Z Gastroenterol. 2002;40 Suppl 1:S57-S61.
Minne, H. W., Begerow, B., & Pfeifer, M. (2002). [Osteoporosis - Evidence based therapy]. Zeitschrift Fur Gastroenterologie, 40 Suppl 1, pp. S57-S61.
Minne HW, Begerow B, Pfeifer M. [Osteoporosis - Evidence Based Therapy]. Z Gastroenterol. 2002;40 Suppl 1:S57-S61. PubMed PMID: 11930292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Osteoporosis - Evidence based therapy]. AU - Minne,H W, AU - Begerow,B, AU - Pfeifer,M, PY - 2002/4/4/pubmed PY - 2002/9/7/medline PY - 2002/4/4/entrez SP - S57 EP - S61 JF - Zeitschrift fur Gastroenterologie JO - Z Gastroenterol VL - 40 Suppl 1 N2 - Osteoporosis therapy has been controversially discussed in the past. In the meantime, several therapeutic options to prevent fractures are available for this disease. With respect to proven fracture benefit, however, the quality of evidence from randomised and controlled clinical trials varies substantially among therapies. From systematic research the best external evidence is available for a supplementation with calcium and vitamin D and a therapy with the bisphosphonates alendronate or risedronate, as well as the SERM raloxifene. For other therapeutic agents like fluorides, vitamin D metabolites, calcitonin and etidronate the quality of evidence is much lower. So far, there is no evidence for other pharmaceutical therapies. Hip protectors are effective in the prevention of hip fractures. SN - 0044-2771 UR - https://www.unboundmedicine.com/medline/citation/11930292/[Osteoporosis___Evidence_based_therapy]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2002-23613 DB - PRIME DP - Unbound Medicine ER -