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Paradoxical responses in a cohort of HIV-1-infected patients with mycobacterial disease.
Int J Tuberc Lung Dis. 2002 Jan; 6(1):71-5.IJ

Abstract

SETTING

Paradoxical worsening or relapse of opportunistic infections has been described after initiation of highly active anti-retroviral therapy (HAART) in human immunodeficiency virus (HIV) infected patients.

DESIGN

Retrospective study of a group of 33 HIV-infected patients with mycobacterial disease analysing the incidence and characteristics of patients with and without paradoxical response after starting HAART and/or mycobacterial treatment.

RESULTS

Nine patients in the group had paradoxical response. No significant difference of baseline characteristics was observed in these patients. The decrease in viral load was significantly greater among patients with paradoxical response than in patients without.

CONCLUSION

No clinical difference was found in the evolution of HIV-infected patients with mycobacterial disease after the resolution of the episode of paradoxical response.

Authors+Show Affiliations

Unidad de Infección VIH, Servicio de Medicina Interna, Hospital Universitario Doce de Octubre, Madrid, Spain. mpomboj@nexo.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11931404

Citation

Olalla, J, et al. "Paradoxical Responses in a Cohort of HIV-1-infected Patients With Mycobacterial Disease." The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease, vol. 6, no. 1, 2002, pp. 71-5.
Olalla J, Pulido F, Rubio R, et al. Paradoxical responses in a cohort of HIV-1-infected patients with mycobacterial disease. Int J Tuberc Lung Dis. 2002;6(1):71-5.
Olalla, J., Pulido, F., Rubio, R., Costa, M. A., Monsalvo, R., Palenque, E., Costa, J. R., & Del, P. A. (2002). Paradoxical responses in a cohort of HIV-1-infected patients with mycobacterial disease. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease, 6(1), 71-5.
Olalla J, et al. Paradoxical Responses in a Cohort of HIV-1-infected Patients With Mycobacterial Disease. Int J Tuberc Lung Dis. 2002;6(1):71-5. PubMed PMID: 11931404.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Paradoxical responses in a cohort of HIV-1-infected patients with mycobacterial disease. AU - Olalla,J, AU - Pulido,F, AU - Rubio,R, AU - Costa,M A, AU - Monsalvo,R, AU - Palenque,E, AU - Costa,J R, AU - Del,Palacio A, PY - 2002/4/5/pubmed PY - 2002/10/3/medline PY - 2002/4/5/entrez SP - 71 EP - 5 JF - The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease JO - Int. J. Tuberc. Lung Dis. VL - 6 IS - 1 N2 - SETTING: Paradoxical worsening or relapse of opportunistic infections has been described after initiation of highly active anti-retroviral therapy (HAART) in human immunodeficiency virus (HIV) infected patients. DESIGN: Retrospective study of a group of 33 HIV-infected patients with mycobacterial disease analysing the incidence and characteristics of patients with and without paradoxical response after starting HAART and/or mycobacterial treatment. RESULTS: Nine patients in the group had paradoxical response. No significant difference of baseline characteristics was observed in these patients. The decrease in viral load was significantly greater among patients with paradoxical response than in patients without. CONCLUSION: No clinical difference was found in the evolution of HIV-infected patients with mycobacterial disease after the resolution of the episode of paradoxical response. SN - 1027-3719 UR - https://www.unboundmedicine.com/medline/citation/11931404/Paradoxical_responses_in_a_cohort_of_HIV_1_infected_patients_with_mycobacterial_disease_ L2 - https://www.ingentaconnect.com/openurl?genre=article&issn=1027-3719&volume=6&issue=1&spage=71&aulast=Olalla DB - PRIME DP - Unbound Medicine ER -