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Blood culture confirmed typhoid fever in a provincial hospital in the Philippines.

Abstract

Epidemiological features of blood culture confirmed typhoid fever and antibiotic sensitivity of isolated Salmonella typhi strains were investigated in Bohol Province in Central Philippines from where no earlier information of these was avialable. Typhoid fever is endemic elsewhere in the Philippines (eg Metropolitan Manila and surroundings) where also multidrug resistant S. typhi strains have been detected. A laboratory for surveillance of invasive bacterial infections was established in a tertiary care government hospital, in Bohol, Central Philippines, in 1994. Patients with suspected typhoid fever or other serious infection were managed and blood cultures from them were taken according to clinicians' judgment. Blood cultures were processed and the isolated bacteria identified using generally accepted methods. S. typhi and other Salmonella isolates were identified using commercial antisera. Patient data were collected from hospital records. Of a total of 4,699 blood cultures done during a period of 3 3/4 years, 1,530 (32%) were requested for suspected typhoid fever. S. typhi was the most common pathogen isolated from 422 patients (8.9%), followed by S. paratyphi A from 55 patients (1%). Most patients were young adults (43%) and school age children (28%). Male:female ratio was 1.5:1. Among the 422 patients, there were 9 (2%) deaths due to typhoid fever, all with complications. All S. typhi isolates were sensitive to chloramphenicol, cotrimoxazole, and ampicillin. Our observation on blood culture confirmed typhoid fever demonstrates its importance as a major infectious disease in Bohol and gives a sound basis for treatment of typhoid patients and for further clinical and epidemiologic studies of typhoid fever and for following antibiotic sensitivity of S. typhi in Bohol and elsewhere in the Philippines.

Authors+Show Affiliations

Governor Celestino Gallares Memorial Hospital, Bohol Province, Philippines. arivac@mozcom.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11944712

Citation

Abucejo, P E., et al. "Blood Culture Confirmed Typhoid Fever in a Provincial Hospital in the Philippines." The Southeast Asian Journal of Tropical Medicine and Public Health, vol. 32, no. 3, 2001, pp. 531-6.
Abucejo PE, Capeding MR, Lupisan SP, et al. Blood culture confirmed typhoid fever in a provincial hospital in the Philippines. Southeast Asian J Trop Med Public Health. 2001;32(3):531-6.
Abucejo, P. E., Capeding, M. R., Lupisan, S. P., Arcay, J., Sombrero, L. T., Ruutu, P., & Herva, E. (2001). Blood culture confirmed typhoid fever in a provincial hospital in the Philippines. The Southeast Asian Journal of Tropical Medicine and Public Health, 32(3), 531-6.
Abucejo PE, et al. Blood Culture Confirmed Typhoid Fever in a Provincial Hospital in the Philippines. Southeast Asian J Trop Med Public Health. 2001;32(3):531-6. PubMed PMID: 11944712.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Blood culture confirmed typhoid fever in a provincial hospital in the Philippines. AU - Abucejo,P E, AU - Capeding,M R, AU - Lupisan,S P, AU - Arcay,J, AU - Sombrero,L T, AU - Ruutu,P, AU - Herva,E, PY - 2002/4/12/pubmed PY - 2002/5/1/medline PY - 2002/4/12/entrez SP - 531 EP - 6 JF - The Southeast Asian journal of tropical medicine and public health JO - Southeast Asian J. Trop. Med. Public Health VL - 32 IS - 3 N2 - Epidemiological features of blood culture confirmed typhoid fever and antibiotic sensitivity of isolated Salmonella typhi strains were investigated in Bohol Province in Central Philippines from where no earlier information of these was avialable. Typhoid fever is endemic elsewhere in the Philippines (eg Metropolitan Manila and surroundings) where also multidrug resistant S. typhi strains have been detected. A laboratory for surveillance of invasive bacterial infections was established in a tertiary care government hospital, in Bohol, Central Philippines, in 1994. Patients with suspected typhoid fever or other serious infection were managed and blood cultures from them were taken according to clinicians' judgment. Blood cultures were processed and the isolated bacteria identified using generally accepted methods. S. typhi and other Salmonella isolates were identified using commercial antisera. Patient data were collected from hospital records. Of a total of 4,699 blood cultures done during a period of 3 3/4 years, 1,530 (32%) were requested for suspected typhoid fever. S. typhi was the most common pathogen isolated from 422 patients (8.9%), followed by S. paratyphi A from 55 patients (1%). Most patients were young adults (43%) and school age children (28%). Male:female ratio was 1.5:1. Among the 422 patients, there were 9 (2%) deaths due to typhoid fever, all with complications. All S. typhi isolates were sensitive to chloramphenicol, cotrimoxazole, and ampicillin. Our observation on blood culture confirmed typhoid fever demonstrates its importance as a major infectious disease in Bohol and gives a sound basis for treatment of typhoid patients and for further clinical and epidemiologic studies of typhoid fever and for following antibiotic sensitivity of S. typhi in Bohol and elsewhere in the Philippines. SN - 0125-1562 UR - https://www.unboundmedicine.com/medline/citation/11944712/Blood_culture_confirmed_typhoid_fever_in_a_provincial_hospital_in_the_Philippines_ L2 - http://www.diseaseinfosearch.org/result/7276 DB - PRIME DP - Unbound Medicine ER -