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Combined intrathecal baclofen and morphine infusion for the treatment of spasticity related pain and central deafferentiation pain.
Acta Neurochir Suppl 2002; 79:75-6AN

Abstract

OBJECTIVES

Complex pain syndromes due to spasticity and central deafferentation often fail to respond to medical therapy and create challenging problems in the pain management. So far, only spasticity associated musculosceletal pain has been reported to respond to intrathecal baclofen application [1, 2].

METHODS

We report the treatment of severe neuropathic pain in a patient with ED and the combined intrathecal application of baclofen and morphine in 5 patients with severe spasticity related pain.

RESULTS

Continuous intrathecal baclofen infusion resulted in a pain free period of 20 months in the patient with ED. Patients with spasticity treated with intrathecal application of baclofen and morphine were pain free for a mean period of 2 years.

CONCLUSION

Intrathecal baclofen and morphine application proved to be effective in spasticity related and central deafferentation pain and should therefore be considered in the management of these patients.

Authors+Show Affiliations

Department of Neurosurgery, Philipps-University Hospital, Marburg, Germany.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11974992

Citation

Gatscher, S, et al. "Combined Intrathecal Baclofen and Morphine Infusion for the Treatment of Spasticity Related Pain and Central Deafferentiation Pain." Acta Neurochirurgica. Supplement, vol. 79, 2002, pp. 75-6.
Gatscher S, Becker R, Uhle E, et al. Combined intrathecal baclofen and morphine infusion for the treatment of spasticity related pain and central deafferentiation pain. Acta Neurochir Suppl. 2002;79:75-6.
Gatscher, S., Becker, R., Uhle, E., & Bertalanffy, H. (2002). Combined intrathecal baclofen and morphine infusion for the treatment of spasticity related pain and central deafferentiation pain. Acta Neurochirurgica. Supplement, 79, pp. 75-6.
Gatscher S, et al. Combined Intrathecal Baclofen and Morphine Infusion for the Treatment of Spasticity Related Pain and Central Deafferentiation Pain. Acta Neurochir Suppl. 2002;79:75-6. PubMed PMID: 11974992.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined intrathecal baclofen and morphine infusion for the treatment of spasticity related pain and central deafferentiation pain. AU - Gatscher,S, AU - Becker,R, AU - Uhle,E, AU - Bertalanffy,H, PY - 2002/4/27/pubmed PY - 2002/10/11/medline PY - 2002/4/27/entrez SP - 75 EP - 6 JF - Acta neurochirurgica. Supplement JO - Acta Neurochir. Suppl. VL - 79 N2 - OBJECTIVES: Complex pain syndromes due to spasticity and central deafferentation often fail to respond to medical therapy and create challenging problems in the pain management. So far, only spasticity associated musculosceletal pain has been reported to respond to intrathecal baclofen application [1, 2]. METHODS: We report the treatment of severe neuropathic pain in a patient with ED and the combined intrathecal application of baclofen and morphine in 5 patients with severe spasticity related pain. RESULTS: Continuous intrathecal baclofen infusion resulted in a pain free period of 20 months in the patient with ED. Patients with spasticity treated with intrathecal application of baclofen and morphine were pain free for a mean period of 2 years. CONCLUSION: Intrathecal baclofen and morphine application proved to be effective in spasticity related and central deafferentation pain and should therefore be considered in the management of these patients. SN - 0065-1419 UR - https://www.unboundmedicine.com/medline/citation/11974992/Combined_intrathecal_baclofen_and_morphine_infusion_for_the_treatment_of_spasticity_related_pain_and_central_deafferentiation_pain_ L2 - http://www.diseaseinfosearch.org/result/6711 DB - PRIME DP - Unbound Medicine ER -