Tags

Type your tag names separated by a space and hit enter

Hyperemesis gravidarum complicated by Wernicke's encephalopathy.
Obstet Gynecol. 2002 May; 99(5 Pt 2):875-7.OG

Abstract

BACKGROUND

Wernicke's encephalopathy is usually associated with alcohol abuse, but can also occur with hyperemesis gravidarum. The effect of delay in thiamine replacement on fetal outcomes is unknown. We present a case of this complication.

CASE

A primipara with hyperemesis was admitted for mental status changes in her 14th week of pregnancy. Physical examination revealed a lethargic patient with ophthalmoplegia, ataxia, and hyporeflexia. Parenteral thiamine therapy was started. The patient improved rapidly although the ataxia persisted. A spontaneous abortion occurred 2 weeks later.

CONCLUSION

Wernicke's encephalopathy can complicate hyperemesis gravidarum. Early thiamine replacement may decrease the chances of spontaneous abortion.

Links

Publisher Full Text
Aggregator Full Text

Authors+Show Affiliations

Spruill SC
Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kuller JA
No affiliation info available

MeSH

Abortion, SpontaneousFemaleHumansHyperemesis GravidarumPregnancyPregnancy ComplicationsPregnancy Trimester, FirstThiamineWernicke Encephalopathy

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

11975941

Citation

Spruill, Steven C., and Jeffrey A. Kuller. "Hyperemesis Gravidarum Complicated By Wernicke's Encephalopathy." Obstetrics and Gynecology, vol. 99, no. 5 Pt 2, 2002, pp. 875-7.
Spruill SC, Kuller JA. Hyperemesis gravidarum complicated by Wernicke's encephalopathy. Obstet Gynecol. 2002;99(5 Pt 2):875-7.
Spruill, S. C., & Kuller, J. A. (2002). Hyperemesis gravidarum complicated by Wernicke's encephalopathy. Obstetrics and Gynecology, 99(5 Pt 2), 875-7.
Spruill SC, Kuller JA. Hyperemesis Gravidarum Complicated By Wernicke's Encephalopathy. Obstet Gynecol. 2002;99(5 Pt 2):875-7. PubMed PMID: 11975941.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hyperemesis gravidarum complicated by Wernicke's encephalopathy. AU - Spruill,Steven C, AU - Kuller,Jeffrey A, PY - 2002/4/27/pubmed PY - 2002/9/18/medline PY - 2002/4/27/entrez SP - 875 EP - 7 JF - Obstetrics and gynecology JO - Obstet Gynecol VL - 99 IS - 5 Pt 2 N2 - BACKGROUND: Wernicke's encephalopathy is usually associated with alcohol abuse, but can also occur with hyperemesis gravidarum. The effect of delay in thiamine replacement on fetal outcomes is unknown. We present a case of this complication. CASE: A primipara with hyperemesis was admitted for mental status changes in her 14th week of pregnancy. Physical examination revealed a lethargic patient with ophthalmoplegia, ataxia, and hyporeflexia. Parenteral thiamine therapy was started. The patient improved rapidly although the ataxia persisted. A spontaneous abortion occurred 2 weeks later. CONCLUSION: Wernicke's encephalopathy can complicate hyperemesis gravidarum. Early thiamine replacement may decrease the chances of spontaneous abortion. SN - 0029-7844 UR - https://www.unboundmedicine.com/medline/citation/11975941/Hyperemesis_gravidarum_complicated_by_Wernicke's_encephalopathy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0029784401016039 DB - PRIME DP - Unbound Medicine ER -