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Prevention of yellow fever in persons traveling to the tropics.
Clin Infect Dis 2002; 34(10):1369-78CI

Abstract

Yellow fever (YF) is a potentially lethal mosquito-borne viral hemorrhagic fever endemic in Africa and South America. Nine million tourists annually arrive in countries where YF is endemic, and fatal cases of YF have occurred recently in travelers. In this article, we review the risk factors for YF during travel and the use of YF 17D vaccine to prevent the disease. Although the vaccine is highly effective and has a long history of safe use, the occurrence of rare, fatal adverse events has raised new concerns. These events should not deter travelers to areas where YF is endemic from being immunized, because the risk of YF infection and illness may be high in rural areas and cannot be easily defined by existing surveillance. To avoid unnecessary vaccination, physicians should vaccinate persons at risk on the basis of knowledge of the epidemiology of the disease, reports of epidemic activity, season, and the likelihood of exposure to vector mosquitoes.

Authors+Show Affiliations

Research and Medical Affairs, Acambis, Cambridge, MA 02139, USA. tom.monath@acambis.comNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

11981733

Citation

Monath, Thomas P., and Martin S. Cetron. "Prevention of Yellow Fever in Persons Traveling to the Tropics." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 34, no. 10, 2002, pp. 1369-78.
Monath TP, Cetron MS. Prevention of yellow fever in persons traveling to the tropics. Clin Infect Dis. 2002;34(10):1369-78.
Monath, T. P., & Cetron, M. S. (2002). Prevention of yellow fever in persons traveling to the tropics. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 34(10), pp. 1369-78.
Monath TP, Cetron MS. Prevention of Yellow Fever in Persons Traveling to the Tropics. Clin Infect Dis. 2002 May 15;34(10):1369-78. PubMed PMID: 11981733.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevention of yellow fever in persons traveling to the tropics. AU - Monath,Thomas P, AU - Cetron,Martin S, Y1 - 2002/04/25/ PY - 2001/11/05/received PY - 2002/01/03/revised PY - 2002/5/1/pubmed PY - 2002/5/17/medline PY - 2002/5/1/entrez SP - 1369 EP - 78 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin. Infect. Dis. VL - 34 IS - 10 N2 - Yellow fever (YF) is a potentially lethal mosquito-borne viral hemorrhagic fever endemic in Africa and South America. Nine million tourists annually arrive in countries where YF is endemic, and fatal cases of YF have occurred recently in travelers. In this article, we review the risk factors for YF during travel and the use of YF 17D vaccine to prevent the disease. Although the vaccine is highly effective and has a long history of safe use, the occurrence of rare, fatal adverse events has raised new concerns. These events should not deter travelers to areas where YF is endemic from being immunized, because the risk of YF infection and illness may be high in rural areas and cannot be easily defined by existing surveillance. To avoid unnecessary vaccination, physicians should vaccinate persons at risk on the basis of knowledge of the epidemiology of the disease, reports of epidemic activity, season, and the likelihood of exposure to vector mosquitoes. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/11981733/full_citation L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/340104 DB - PRIME DP - Unbound Medicine ER -