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Myeloma-associated systemic amyloidosis presenting with acquired digital cutis laxa-like changes.
Australas J Dermatol. 2002 May; 43(2):144-6.AJ

Abstract

A 59-year-old woman presented with a 6-year history of lax skin on the distal fingers of both hands, as well as a recent increase in the size of her tongue. Histopathology of skin from her distal finger showed amyloid deposition and bone marrow biopsy revealed an underlying plasma cell dyscrasia. Initial treatment with cyclophosphamide, vincristine, adriamycin and methylprednisolone has produced a significant reduction in the swelling of both her hands and tongue. Acquired digital cutis laxa-like changes are a rare cutaneous manifestation of systemic amyloidosis.

Authors+Show Affiliations

Department of Dermatology, Royal Brisbane Hospital, Post Office, Herston, Queensland 4029, Australia. tdicker@bigpond.net.auNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

11982574

Citation

Dicker, Tony J., et al. "Myeloma-associated Systemic Amyloidosis Presenting With Acquired Digital Cutis Laxa-like Changes." The Australasian Journal of Dermatology, vol. 43, no. 2, 2002, pp. 144-6.
Dicker TJ, Morton J, Williamson RM, et al. Myeloma-associated systemic amyloidosis presenting with acquired digital cutis laxa-like changes. Australas J Dermatol. 2002;43(2):144-6.
Dicker, T. J., Morton, J., Williamson, R. M., & Chick, J. (2002). Myeloma-associated systemic amyloidosis presenting with acquired digital cutis laxa-like changes. The Australasian Journal of Dermatology, 43(2), 144-6.
Dicker TJ, et al. Myeloma-associated Systemic Amyloidosis Presenting With Acquired Digital Cutis Laxa-like Changes. Australas J Dermatol. 2002;43(2):144-6. PubMed PMID: 11982574.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Myeloma-associated systemic amyloidosis presenting with acquired digital cutis laxa-like changes. AU - Dicker,Tony J, AU - Morton,James, AU - Williamson,Richard M, AU - Chick,Jeff, PY - 2002/5/2/pubmed PY - 2002/6/12/medline PY - 2002/5/2/entrez SP - 144 EP - 6 JF - The Australasian journal of dermatology JO - Australas. J. Dermatol. VL - 43 IS - 2 N2 - A 59-year-old woman presented with a 6-year history of lax skin on the distal fingers of both hands, as well as a recent increase in the size of her tongue. Histopathology of skin from her distal finger showed amyloid deposition and bone marrow biopsy revealed an underlying plasma cell dyscrasia. Initial treatment with cyclophosphamide, vincristine, adriamycin and methylprednisolone has produced a significant reduction in the swelling of both her hands and tongue. Acquired digital cutis laxa-like changes are a rare cutaneous manifestation of systemic amyloidosis. SN - 0004-8380 UR - https://www.unboundmedicine.com/medline/citation/11982574/Myeloma_associated_systemic_amyloidosis_presenting_with_acquired_digital_cutis_laxa_like_changes_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0004-8380&date=2002&volume=43&issue=2&spage=144 DB - PRIME DP - Unbound Medicine ER -