Tags

Type your tag names separated by a space and hit enter

Papillary neoplasms of the breast: clues in fine needle aspiration cytology.
Cytopathology. 2002 Feb; 13(1):22-30.C

Abstract

Papillary neoplasms of the breast include a wide spectrum of mammary lesions. The differential diagnosis of benign and malignant lesions can be problematic not only cytologically, but also histopathologically. Aspiration smears can demonstrate that cytological differentiation is feasible. A retrospective study of 30 cases of papillary tumour of the breast, 15 papillary carcinomas and 15 papillomas, was performed to find the cytological differences between the pathologies. Cytological samples of papillary carcinomas were characterized by an abundance of cellular material, three-dimensional papillary clusters without fibrovascular connective tissue cores, small papillae arranged in cell balls, tall columnar cells and isolated naked nuclei. Numerous haemosiderin-laden macrophages were seen. There were no eosinophilic bipolar cytoplasmic granules, bipolar naked nuclei or apocrine metaplasia. In the papillomas there was less material; the papillae had cohesive stalks surrounded by columnar cells in a honeycomb pattern. We also found fewer small papillae and isolated columnar cells. In addition, the presence of apocrine metaplasia and bipolar naked nuclei was noted. We suggest that papillary carcinoma of the breast can be diagnosed by cytology and differentiated from papilloma.

Authors+Show Affiliations

Departamento de Patologia, Universidad de Zaragoza, Spain.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

11985565

Citation

Gomez-Aracil, V, et al. "Papillary Neoplasms of the Breast: Clues in Fine Needle Aspiration Cytology." Cytopathology : Official Journal of the British Society for Clinical Cytology, vol. 13, no. 1, 2002, pp. 22-30.
Gomez-Aracil V, Mayayo E, Azua J, et al. Papillary neoplasms of the breast: clues in fine needle aspiration cytology. Cytopathology. 2002;13(1):22-30.
Gomez-Aracil, V., Mayayo, E., Azua, J., & Arraiza, A. (2002). Papillary neoplasms of the breast: clues in fine needle aspiration cytology. Cytopathology : Official Journal of the British Society for Clinical Cytology, 13(1), 22-30.
Gomez-Aracil V, et al. Papillary Neoplasms of the Breast: Clues in Fine Needle Aspiration Cytology. Cytopathology. 2002;13(1):22-30. PubMed PMID: 11985565.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Papillary neoplasms of the breast: clues in fine needle aspiration cytology. AU - Gomez-Aracil,V, AU - Mayayo,E, AU - Azua,J, AU - Arraiza,A, PY - 2002/5/3/pubmed PY - 2002/9/6/medline PY - 2002/5/3/entrez SP - 22 EP - 30 JF - Cytopathology : official journal of the British Society for Clinical Cytology JO - Cytopathology VL - 13 IS - 1 N2 - Papillary neoplasms of the breast include a wide spectrum of mammary lesions. The differential diagnosis of benign and malignant lesions can be problematic not only cytologically, but also histopathologically. Aspiration smears can demonstrate that cytological differentiation is feasible. A retrospective study of 30 cases of papillary tumour of the breast, 15 papillary carcinomas and 15 papillomas, was performed to find the cytological differences between the pathologies. Cytological samples of papillary carcinomas were characterized by an abundance of cellular material, three-dimensional papillary clusters without fibrovascular connective tissue cores, small papillae arranged in cell balls, tall columnar cells and isolated naked nuclei. Numerous haemosiderin-laden macrophages were seen. There were no eosinophilic bipolar cytoplasmic granules, bipolar naked nuclei or apocrine metaplasia. In the papillomas there was less material; the papillae had cohesive stalks surrounded by columnar cells in a honeycomb pattern. We also found fewer small papillae and isolated columnar cells. In addition, the presence of apocrine metaplasia and bipolar naked nuclei was noted. We suggest that papillary carcinoma of the breast can be diagnosed by cytology and differentiated from papilloma. SN - 0956-5507 UR - https://www.unboundmedicine.com/medline/citation/11985565/Papillary_neoplasms_of_the_breast:_clues_in_fine_needle_aspiration_cytology_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0956-5507&date=2002&volume=13&issue=1&spage=22 DB - PRIME DP - Unbound Medicine ER -