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Physical activity and coronary event incidence in Northern Ireland and France: the Prospective Epidemiological Study of Myocardial Infarction (PRIME).
Circulation 2002; 105(19):2247-52Circ

Abstract

BACKGROUND

The influence of physical activity on the incidence of angina pectoris and hard coronary events (myocardial infarction and coronary deaths) was examined in Northern Ireland and France at contrasting risk for coronary heart disease (CHD) and with different physical activity patterns.

METHODS AND RESULTS

Participants of the Prospective Epidemiological Study of Myocardial Infarction (PRIME) (n=9758; age, 50 to 59 years), free of CHD at baseline, were followed up for 5 years: 167 hard CHD and 154 angina events were recorded. Net energy expenditure (EE) as the result of physical activity was assessed by means of the MONICA Optional Study of Physical Activity Questionnaire (MOSPA-Q). Leisure-time physical activity EE was calculated; subjects were also categorized as to whether they performed high-intensity leisure-time activities or walked or cycled to work. After multivariate adjustment, leisure-time physical activity EE was associated with a lower risk of hard CHD events (P<0.04), whereas walking or cycling to work was not independently related to hard CHD events. No interaction by country was found. The beneficial effect of leisure-time physical activity was also present among subjects who did not report high-intensity activities (P<0.04), with similar results in France and Northern Ireland. In contrast, an increasing level of leisure-time physical activity was associated with a higher risk of angina in both countries.

CONCLUSIONS

These data indicate a beneficial effect of leisure-time physical activity EE on hard CHD incidence in middle-aged men, which could partly explain the unfavorable rate of CHD in Northern Ireland. The higher level of leisure-time activities in France could, in part, explain its lower rate of CHD.

Authors+Show Affiliations

Laboratoire d'Epidémiologie et de Santé Publique, Strasbourg, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12010905

Citation

Wagner, Aline, et al. "Physical Activity and Coronary Event Incidence in Northern Ireland and France: the Prospective Epidemiological Study of Myocardial Infarction (PRIME)." Circulation, vol. 105, no. 19, 2002, pp. 2247-52.
Wagner A, Simon C, Evans A, et al. Physical activity and coronary event incidence in Northern Ireland and France: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Circulation. 2002;105(19):2247-52.
Wagner, A., Simon, C., Evans, A., Ferrières, J., Montaye, M., Ducimetière, P., & Arveiler, D. (2002). Physical activity and coronary event incidence in Northern Ireland and France: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Circulation, 105(19), pp. 2247-52.
Wagner A, et al. Physical Activity and Coronary Event Incidence in Northern Ireland and France: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Circulation. 2002 May 14;105(19):2247-52. PubMed PMID: 12010905.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Physical activity and coronary event incidence in Northern Ireland and France: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). AU - Wagner,Aline, AU - Simon,Chantal, AU - Evans,Alun, AU - Ferrières,Jean, AU - Montaye,Michèle, AU - Ducimetière,Pierre, AU - Arveiler,Dominique, PY - 2002/5/16/pubmed PY - 2002/5/25/medline PY - 2002/5/16/entrez SP - 2247 EP - 52 JF - Circulation JO - Circulation VL - 105 IS - 19 N2 - BACKGROUND: The influence of physical activity on the incidence of angina pectoris and hard coronary events (myocardial infarction and coronary deaths) was examined in Northern Ireland and France at contrasting risk for coronary heart disease (CHD) and with different physical activity patterns. METHODS AND RESULTS: Participants of the Prospective Epidemiological Study of Myocardial Infarction (PRIME) (n=9758; age, 50 to 59 years), free of CHD at baseline, were followed up for 5 years: 167 hard CHD and 154 angina events were recorded. Net energy expenditure (EE) as the result of physical activity was assessed by means of the MONICA Optional Study of Physical Activity Questionnaire (MOSPA-Q). Leisure-time physical activity EE was calculated; subjects were also categorized as to whether they performed high-intensity leisure-time activities or walked or cycled to work. After multivariate adjustment, leisure-time physical activity EE was associated with a lower risk of hard CHD events (P<0.04), whereas walking or cycling to work was not independently related to hard CHD events. No interaction by country was found. The beneficial effect of leisure-time physical activity was also present among subjects who did not report high-intensity activities (P<0.04), with similar results in France and Northern Ireland. In contrast, an increasing level of leisure-time physical activity was associated with a higher risk of angina in both countries. CONCLUSIONS: These data indicate a beneficial effect of leisure-time physical activity EE on hard CHD incidence in middle-aged men, which could partly explain the unfavorable rate of CHD in Northern Ireland. The higher level of leisure-time activities in France could, in part, explain its lower rate of CHD. SN - 1524-4539 UR - https://www.unboundmedicine.com/medline/citation/12010905/Physical_activity_and_coronary_event_incidence_in_Northern_Ireland_and_France:_the_Prospective_Epidemiological_Study_of_Myocardial_Infarction__PRIME__ L2 - http://www.ahajournals.org/doi/full/10.1161/01.cir.0000016345.58696.4f?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -