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[Diagnosis and treatment of Lewy body dementia].
Ugeskr Laeger. 2002 Apr 29; 164(18):2383-6.UL

Abstract

Dementia with Lewy bodies (DLB) has recently gained recognition as a separate disease. Lewy bodies are pathoanatomical inclusion bodies in the CNS. They are well known as part of Parkinson's disease where they are present mainly in the substantia nigra, and they are also found in large numbers in the neocortex. It is still an unanswered question why Lewy bodies are formed, but their appearance is connected with cellular degeneration of unknown aetiology. Neuropathological investigations of dementia populations show that DLB accounts for 12-36%, which places it as the second most frequent dementia disease after Alzheimer's disease (AD) with a frequency close to that of vascular dementia. This article reviews the development of the term DLB and describes the clinical characteristics, including the neuropsychological symptom profile, which can contribute to the diagnostic discrimination between DLB and AD. Furthermore, relevant treatment possibilities are discussed.

Authors+Show Affiliations

H:S Kommunehospitalet, center for forskning og udvikling på aeldreområdet, neurologisk afdeling, Amtssygehuset i Gentofte.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

dan

PubMed ID

12024840

Citation

Madsen, Anne-Mette Guldberg, et al. "[Diagnosis and Treatment of Lewy Body Dementia]." Ugeskrift for Laeger, vol. 164, no. 18, 2002, pp. 2383-6.
Madsen AM, Lomholt RK, Djernes JK. [Diagnosis and treatment of Lewy body dementia]. Ugeskr Laeger. 2002;164(18):2383-6.
Madsen, A. M., Lomholt, R. K., & Djernes, J. K. (2002). [Diagnosis and treatment of Lewy body dementia]. Ugeskrift for Laeger, 164(18), 2383-6.
Madsen AM, Lomholt RK, Djernes JK. [Diagnosis and Treatment of Lewy Body Dementia]. Ugeskr Laeger. 2002 Apr 29;164(18):2383-6. PubMed PMID: 12024840.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Diagnosis and treatment of Lewy body dementia]. AU - Madsen,Anne-Mette Guldberg, AU - Lomholt,Rikke Kirstine, AU - Djernes,Jens Kronborg, PY - 2002/5/25/pubmed PY - 2002/7/19/medline PY - 2002/5/25/entrez SP - 2383 EP - 6 JF - Ugeskrift for laeger JO - Ugeskr Laeger VL - 164 IS - 18 N2 - Dementia with Lewy bodies (DLB) has recently gained recognition as a separate disease. Lewy bodies are pathoanatomical inclusion bodies in the CNS. They are well known as part of Parkinson's disease where they are present mainly in the substantia nigra, and they are also found in large numbers in the neocortex. It is still an unanswered question why Lewy bodies are formed, but their appearance is connected with cellular degeneration of unknown aetiology. Neuropathological investigations of dementia populations show that DLB accounts for 12-36%, which places it as the second most frequent dementia disease after Alzheimer's disease (AD) with a frequency close to that of vascular dementia. This article reviews the development of the term DLB and describes the clinical characteristics, including the neuropsychological symptom profile, which can contribute to the diagnostic discrimination between DLB and AD. Furthermore, relevant treatment possibilities are discussed. SN - 0041-5782 UR - https://www.unboundmedicine.com/medline/citation/12024840/[Diagnosis_and_treatment_of_Lewy_body_dementia]_ L2 - https://www.diseaseinfosearch.org/result/4215 DB - PRIME DP - Unbound Medicine ER -