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Practical approaches to migraine management.
CNS Drugs 2002; 16(6):385-403CD

Abstract

Migraine is a recurrent clinical syndrome characterised by combinations of neurological, gastrointestinal and autonomic manifestations. The exact pathophysiological disturbances that occur with migraine have yet to be elucidated; however, cervico-trigemino-vascular dysfunctions appear to be the primary cause. Despite advances in the understanding of the pathophysiology of migraine and new effective treatment options, migraine remains an under-diagnosed, under-treated and poorly treated health condition. Most patients will unsuccessfully attempt to treat their headaches with over-the-counter medications. Few well designed, placebo-controlled studies are available to guide physicians in medication selection. Recently published evidence-based guidelines advocate migraine-specific drugs, such as serotonin 5-HT(1B/1D) agonists (the 'triptans') and dihydroergotamine mesylate, for patients experiencing moderate to severe migraine attacks. Additional headache attack therapy options include other ergotamine derivatives, phenothiazines, nonsteroidal anti-inflammatory agents and opioids. Preventative medication therapy is indicated for patients experiencing frequent and/or refractory attacks.

Authors+Show Affiliations

Diamond Inpatient Headache Unit, Diamond Headache Clinic, St. Joseph Hospital, and Finch University of Health Sciences/The Chicago Medical School, North Chicago, Chicago, Illinois 60614, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

12027785

Citation

Diamond, Seymour, and Richard Wenzel. "Practical Approaches to Migraine Management." CNS Drugs, vol. 16, no. 6, 2002, pp. 385-403.
Diamond S, Wenzel R. Practical approaches to migraine management. CNS Drugs. 2002;16(6):385-403.
Diamond, S., & Wenzel, R. (2002). Practical approaches to migraine management. CNS Drugs, 16(6), pp. 385-403.
Diamond S, Wenzel R. Practical Approaches to Migraine Management. CNS Drugs. 2002;16(6):385-403. PubMed PMID: 12027785.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Practical approaches to migraine management. AU - Diamond,Seymour, AU - Wenzel,Richard, PY - 2002/5/25/pubmed PY - 2002/7/20/medline PY - 2002/5/25/entrez SP - 385 EP - 403 JF - CNS drugs JO - CNS Drugs VL - 16 IS - 6 N2 - Migraine is a recurrent clinical syndrome characterised by combinations of neurological, gastrointestinal and autonomic manifestations. The exact pathophysiological disturbances that occur with migraine have yet to be elucidated; however, cervico-trigemino-vascular dysfunctions appear to be the primary cause. Despite advances in the understanding of the pathophysiology of migraine and new effective treatment options, migraine remains an under-diagnosed, under-treated and poorly treated health condition. Most patients will unsuccessfully attempt to treat their headaches with over-the-counter medications. Few well designed, placebo-controlled studies are available to guide physicians in medication selection. Recently published evidence-based guidelines advocate migraine-specific drugs, such as serotonin 5-HT(1B/1D) agonists (the 'triptans') and dihydroergotamine mesylate, for patients experiencing moderate to severe migraine attacks. Additional headache attack therapy options include other ergotamine derivatives, phenothiazines, nonsteroidal anti-inflammatory agents and opioids. Preventative medication therapy is indicated for patients experiencing frequent and/or refractory attacks. SN - 1172-7047 UR - https://www.unboundmedicine.com/medline/citation/12027785/Practical_approaches_to_migraine_management_ L2 - https://dx.doi.org/10.2165/00023210-200216060-00003 DB - PRIME DP - Unbound Medicine ER -