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New sesquiterpenes from Ferula ferulaeoides (Steud.) Korovin. VI. Isolation and identification of three new dihydrofuro[2,3-b]chromones.
Chem Pharm Bull (Tokyo). 2002 May; 50(5):675-7.CP

Abstract

Three novel 2-prenyl-dihydrofurochromone-type sesquiterpenoid derivatives, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[2,3-b]chromone, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E),7-pentenyl]-furo[2,3-b]chromone, and 2,3-dihydro-7-hydroxy-2R*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E),7-pentenyl]-furo[2,3-b]chromone, were isolated from the roots of Ferula ferulaeoides. The structures were established by comprehensive spectral analysis. The biosynthetic pathway leading to these 2-prenyl-dihydrofurochromone-type sesquiterpenoids is proposed based on their structures.

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Authors+Show Affiliations

Nagatsu A
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
Isaka K
No affiliation info available
Kojima K
No affiliation info available
Ondognii P
No affiliation info available
Zevgeegiin O
No affiliation info available
Gombosurengyin P
No affiliation info available
Davgiin K
No affiliation info available
Irfan B
No affiliation info available
Iqubal CM
No affiliation info available
Ogihara Y
No affiliation info available

MeSH

Asia, CentralChromonesFerulaMagnetic Resonance SpectroscopyMongoliaPlant RootsPlants, MedicinalSesquiterpenes

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12036029

Citation

Nagatsu, Akito, et al. "New Sesquiterpenes From Ferula Ferulaeoides (Steud.) Korovin. VI. Isolation and Identification of Three New Dihydrofuro[2,3-b]chromones." Chemical & Pharmaceutical Bulletin, vol. 50, no. 5, 2002, pp. 675-7.
Nagatsu A, Isaka K, Kojima K, et al. New sesquiterpenes from Ferula ferulaeoides (Steud.) Korovin. VI. Isolation and identification of three new dihydrofuro[2,3-b]chromones. Chem Pharm Bull (Tokyo). 2002;50(5):675-7.
Nagatsu, A., Isaka, K., Kojima, K., Ondognii, P., Zevgeegiin, O., Gombosurengyin, P., Davgiin, K., Irfan, B., Iqubal, C. M., & Ogihara, Y. (2002). New sesquiterpenes from Ferula ferulaeoides (Steud.) Korovin. VI. Isolation and identification of three new dihydrofuro[2,3-b]chromones. Chemical & Pharmaceutical Bulletin, 50(5), 675-7.
Nagatsu A, et al. New Sesquiterpenes From Ferula Ferulaeoides (Steud.) Korovin. VI. Isolation and Identification of Three New Dihydrofuro[2,3-b]chromones. Chem Pharm Bull (Tokyo). 2002;50(5):675-7. PubMed PMID: 12036029.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New sesquiterpenes from Ferula ferulaeoides (Steud.) Korovin. VI. Isolation and identification of three new dihydrofuro[2,3-b]chromones. AU - Nagatsu,Akito, AU - Isaka,Kimio, AU - Kojima,Keisuke, AU - Ondognii,Purev, AU - Zevgeegiin,Oyun, AU - Gombosurengyin,Purevsuren, AU - Davgiin,Khishgee, AU - Irfan,Baig, AU - Iqubal,Choudhary Muhammad, AU - Ogihara,Yukio, PY - 2002/5/31/pubmed PY - 2002/11/30/medline PY - 2002/5/31/entrez SP - 675 EP - 7 JF - Chemical & pharmaceutical bulletin JO - Chem Pharm Bull (Tokyo) VL - 50 IS - 5 N2 - Three novel 2-prenyl-dihydrofurochromone-type sesquiterpenoid derivatives, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[2,3-b]chromone, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E),7-pentenyl]-furo[2,3-b]chromone, and 2,3-dihydro-7-hydroxy-2R*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E),7-pentenyl]-furo[2,3-b]chromone, were isolated from the roots of Ferula ferulaeoides. The structures were established by comprehensive spectral analysis. The biosynthetic pathway leading to these 2-prenyl-dihydrofurochromone-type sesquiterpenoids is proposed based on their structures. SN - 0009-2363 UR - https://www.unboundmedicine.com/medline/citation/12036029/New_sesquiterpenes_from_Ferula_ferulaeoides__Steud___Korovin__VI__Isolation_and_identification_of_three_new_dihydrofuro[23_b]chromones_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/cpb/50.675?from=PubMed DB - PRIME DP - Unbound Medicine ER -