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The effect of wheat bran particle size on laxation and colonic fermentation.
J Am Coll Nutr. 1999 Aug; 18(4):339-45.JA

Abstract

OBJECTIVE

Due to perceived inferior fecal bulking ability, finely ground wheat bran is not recommended for treatment of colonic disorders, despite possible short chain fatty acid generation with potential benefits for colonic mucosal health. We therefore tested the effects of very fine particle size wheat bran on colonic function.

METHODS

Two studies, each with three phases, were undertaken in healthy subjects in a randomized crossover design. In one study (metabolic, n=23) subjects took three diets containing either an additional 19 g/d dietary fiber with mean particle size (MPS) 50 microm or 758 microm in bread or a control low fiber bread. In the other study where the supplement was provided as a breakfast cereal (ad libitum, n=24) the respective wheat bran MPS were 692 microm and 1158 microm and the control was low fiber. Fecal collections were obtained during the last week of each diet. In the metabolic study, fecal short chain fatty acids were measured and 12-hour breath gas collections obtained.

RESULTS

In both studies, wheat bran supplements significantly increased fecal bulk compared to the control (p<0.004), with no significant differences between brans of different particle size and no differences in fecal water content. However, higher fecal butyrate concentrations (p<0.007), butyrate output and breath CH4 levels (p=0.025) were seen on the low MPS wheat bran compared to the other two treatments, suggesting increased bacterial fermentation.

CONCLUSIONS

Fine MPS wheat bran is an effective fecal bulking agent and may have added advantages if increased butyrate concentrations promote colonic mucosal integrity.

Authors+Show Affiliations

Clinical Nutrition and Risk Factor Modification Center, St. Michael's Hospital, Toronto, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12038477

Citation

Jenkins, D J., et al. "The Effect of Wheat Bran Particle Size On Laxation and Colonic Fermentation." Journal of the American College of Nutrition, vol. 18, no. 4, 1999, pp. 339-45.
Jenkins DJ, Kendall CW, Vuksan V, et al. The effect of wheat bran particle size on laxation and colonic fermentation. J Am Coll Nutr. 1999;18(4):339-45.
Jenkins, D. J., Kendall, C. W., Vuksan, V., Augustin, L. S., Li, Y. M., Lee, B., Mehling, C. C., Parker, T., Faulkner, D., Seyler, H., Vidgen, E., & Fulgoni, V. (1999). The effect of wheat bran particle size on laxation and colonic fermentation. Journal of the American College of Nutrition, 18(4), 339-45.
Jenkins DJ, et al. The Effect of Wheat Bran Particle Size On Laxation and Colonic Fermentation. J Am Coll Nutr. 1999;18(4):339-45. PubMed PMID: 12038477.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of wheat bran particle size on laxation and colonic fermentation. AU - Jenkins,D J, AU - Kendall,C W, AU - Vuksan,V, AU - Augustin,L S, AU - Li,Y M, AU - Lee,B, AU - Mehling,C C, AU - Parker,T, AU - Faulkner,D, AU - Seyler,H, AU - Vidgen,E, AU - Fulgoni,V, PY - 2002/6/1/pubmed PY - 2002/8/22/medline PY - 2002/6/1/entrez SP - 339 EP - 45 JF - Journal of the American College of Nutrition JO - J Am Coll Nutr VL - 18 IS - 4 N2 - OBJECTIVE: Due to perceived inferior fecal bulking ability, finely ground wheat bran is not recommended for treatment of colonic disorders, despite possible short chain fatty acid generation with potential benefits for colonic mucosal health. We therefore tested the effects of very fine particle size wheat bran on colonic function. METHODS: Two studies, each with three phases, were undertaken in healthy subjects in a randomized crossover design. In one study (metabolic, n=23) subjects took three diets containing either an additional 19 g/d dietary fiber with mean particle size (MPS) 50 microm or 758 microm in bread or a control low fiber bread. In the other study where the supplement was provided as a breakfast cereal (ad libitum, n=24) the respective wheat bran MPS were 692 microm and 1158 microm and the control was low fiber. Fecal collections were obtained during the last week of each diet. In the metabolic study, fecal short chain fatty acids were measured and 12-hour breath gas collections obtained. RESULTS: In both studies, wheat bran supplements significantly increased fecal bulk compared to the control (p<0.004), with no significant differences between brans of different particle size and no differences in fecal water content. However, higher fecal butyrate concentrations (p<0.007), butyrate output and breath CH4 levels (p=0.025) were seen on the low MPS wheat bran compared to the other two treatments, suggesting increased bacterial fermentation. CONCLUSIONS: Fine MPS wheat bran is an effective fecal bulking agent and may have added advantages if increased butyrate concentrations promote colonic mucosal integrity. SN - 0731-5724 UR - https://www.unboundmedicine.com/medline/citation/12038477/The_effect_of_wheat_bran_particle_size_on_laxation_and_colonic_fermentation_ L2 - https://www.tandfonline.com/doi/full/10.1080/07315724.1999.10718873 DB - PRIME DP - Unbound Medicine ER -