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[General antibiotic therapy in acne].
Rev Prat. 2002 Apr 15; 52(8):841-3.RP

Abstract

The primary indication for systemic antibiotics is acute therapy for moderate-to-severe inflammatory acne. The preferred agents include tetracyclines and derivatives; macrolides, co-trimoxazole, and trimethoprim may represent acceptable alternatives. Antibiotics act mainly on inflammatory lesions (papules and pustules) and are only slightly comedolytic. Oral antibiotics reduce the number of Propionibacterium acnes. In addition, they have an anti-inflammatory activity. The side effects associated with oral antibiotics for acne depend on the drug; however, severe side effects are not common. Resistant strains of Propionibacterium acnes to antibiotics are increasing. Thus, general guidelines are useful when utilizing oral antibiotic therapy in acne.

Authors+Show Affiliations

Dréno B
Clinique dermatologique Centre hospitalier universitaire Hôtel-Dieu, 44093 Nantes. bdreno@wanadoo.fr

MeSH

Acne VulgarisAdministration, OralAnti-Bacterial AgentsDrug ResistanceHumansInflammationPropionibacterium acnes

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

12053791

Citation

Dréno, Brigitte. "[General Antibiotic Therapy in Acne]." La Revue Du Praticien, vol. 52, no. 8, 2002, pp. 841-3.
Dréno B. [General antibiotic therapy in acne]. Rev Prat. 2002;52(8):841-3.
Dréno, B. (2002). [General antibiotic therapy in acne]. La Revue Du Praticien, 52(8), 841-3.
Dréno B. [General Antibiotic Therapy in Acne]. Rev Prat. 2002 Apr 15;52(8):841-3. PubMed PMID: 12053791.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [General antibiotic therapy in acne]. A1 - Dréno,Brigitte, PY - 2002/6/11/pubmed PY - 2002/7/18/medline PY - 2002/6/11/entrez SP - 841 EP - 3 JF - La Revue du praticien JO - Rev Prat VL - 52 IS - 8 N2 - The primary indication for systemic antibiotics is acute therapy for moderate-to-severe inflammatory acne. The preferred agents include tetracyclines and derivatives; macrolides, co-trimoxazole, and trimethoprim may represent acceptable alternatives. Antibiotics act mainly on inflammatory lesions (papules and pustules) and are only slightly comedolytic. Oral antibiotics reduce the number of Propionibacterium acnes. In addition, they have an anti-inflammatory activity. The side effects associated with oral antibiotics for acne depend on the drug; however, severe side effects are not common. Resistant strains of Propionibacterium acnes to antibiotics are increasing. Thus, general guidelines are useful when utilizing oral antibiotic therapy in acne. SN - 0035-2640 UR - https://www.unboundmedicine.com/medline/citation/12053791/[General_antibiotic_therapy_in_acne]_ L2 - https://medlineplus.gov/acne.html DB - PRIME DP - Unbound Medicine ER -