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Clinical trials in healthy volunteers with the new purified chick embryo cell rabies vaccine for man.
J Commun Dis. 1984 Mar; 16(1):61-9.JC

Abstract

Behringwerke has developed the new, safe and economical purified chick embryo cell (PCEC) rabies vaccine. Due to the purification by zonal centrifugation the compatibility of this vaccine is excellent. Among 933 vaccinations in 219 healthy volunteers the only side-effect was mild pain at the injection-site in 17 vaccinations (1.7 per cent). The sero-conversion of PCEC rabies vaccine was 100 per cent in the tested healthy volunteers. The kinetics of antibody induction after PCEC rabies vaccine is comparable to antibody induction after HDC rabies vaccine. PCEC rabies vaccine induces cellular immunity as measured in lymphocyte transformation test, but no interferon activity.

Authors+Show Affiliations

Behring Werke AG, Marburg, West Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

12055789

Citation

Bijok, U, et al. "Clinical Trials in Healthy Volunteers With the New Purified Chick Embryo Cell Rabies Vaccine for Man." The Journal of Communicable Diseases, vol. 16, no. 1, 1984, pp. 61-9.
Bijok U, Barth R, Gruschkau H, et al. Clinical trials in healthy volunteers with the new purified chick embryo cell rabies vaccine for man. J Commun Dis. 1984;16(1):61-9.
Bijok, U., Barth, R., Gruschkau, H., Vodopija, I., Smerdel, S., Kukla, H., & Geursen, R. (1984). Clinical trials in healthy volunteers with the new purified chick embryo cell rabies vaccine for man. The Journal of Communicable Diseases, 16(1), 61-9.
Bijok U, et al. Clinical Trials in Healthy Volunteers With the New Purified Chick Embryo Cell Rabies Vaccine for Man. J Commun Dis. 1984;16(1):61-9. PubMed PMID: 12055789.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical trials in healthy volunteers with the new purified chick embryo cell rabies vaccine for man. AU - Bijok,U, AU - Barth,R, AU - Gruschkau,H, AU - Vodopija,I, AU - Smerdel,S, AU - Kukla,H, AU - Geursen,R, PY - 1984/3/1/pubmed PY - 2002/8/3/medline PY - 1984/3/1/entrez SP - 61 EP - 9 JF - The Journal of communicable diseases JO - J Commun Dis VL - 16 IS - 1 N2 - Behringwerke has developed the new, safe and economical purified chick embryo cell (PCEC) rabies vaccine. Due to the purification by zonal centrifugation the compatibility of this vaccine is excellent. Among 933 vaccinations in 219 healthy volunteers the only side-effect was mild pain at the injection-site in 17 vaccinations (1.7 per cent). The sero-conversion of PCEC rabies vaccine was 100 per cent in the tested healthy volunteers. The kinetics of antibody induction after PCEC rabies vaccine is comparable to antibody induction after HDC rabies vaccine. PCEC rabies vaccine induces cellular immunity as measured in lymphocyte transformation test, but no interferon activity. SN - 0019-5138 UR - https://www.unboundmedicine.com/medline/citation/12055789/Clinical_trials_in_healthy_volunteers_with_the_new_purified_chick_embryo_cell_rabies_vaccine_for_man_ L2 - http://www.diseaseinfosearch.org/result/6131 DB - PRIME DP - Unbound Medicine ER -