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Synthesis and antimicrobial evaluation of new phenoxyacetamide derivatives.
Boll Chim Farm. 2002 Jan-Feb; 141(1):3-7.BC

Abstract

New N-(5-methylisoxazol-3-yl)-2 or 3 or 4-(phenoxyacetamido)benzamides 6a-t were synthesized and tested for their in vitro antimicrobial activity against gram positive (Staphylococcus aureus ATCC 25923) and gram negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853) bacteria as well as fungi (Candida albicans ATCC 10231, Candida tropicalis ATCC 13803 and Cryptococcus neoformans ATCC 90112). Compounds 6 were devoid of antibacterial as well as antifungal activities at maximum tested concentrations of 50 micrograms/ml for bacteria and 100 micrograms/ml for yeast.

Authors+Show Affiliations

Raffa D
Università degli Studi di Palermo, Dipartimento di Chimica e Tecnologie Farmaceutiche, via Archirafi 32, 90123 Palermo, Italy.
Migliara O
No affiliation info available
Daidone G
No affiliation info available
Maggio B
No affiliation info available
Schillaci D
No affiliation info available

MeSH

AcetamidesAnti-Bacterial AgentsAnti-Infective AgentsBacteriaFungiGram-Negative BacteriaGram-Positive BacteriaIndicators and ReagentsMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsPhenyl Ethers

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12064055

Citation

Raffa, D, et al. "Synthesis and Antimicrobial Evaluation of New Phenoxyacetamide Derivatives." Bollettino Chimico Farmaceutico, vol. 141, no. 1, 2002, pp. 3-7.
Raffa D, Migliara O, Daidone G, et al. Synthesis and antimicrobial evaluation of new phenoxyacetamide derivatives. Boll Chim Farm. 2002;141(1):3-7.
Raffa, D., Migliara, O., Daidone, G., Maggio, B., & Schillaci, D. (2002). Synthesis and antimicrobial evaluation of new phenoxyacetamide derivatives. Bollettino Chimico Farmaceutico, 141(1), 3-7.
Raffa D, et al. Synthesis and Antimicrobial Evaluation of New Phenoxyacetamide Derivatives. Boll Chim Farm. 2002 Jan-Feb;141(1):3-7. PubMed PMID: 12064055.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis and antimicrobial evaluation of new phenoxyacetamide derivatives. AU - Raffa,D, AU - Migliara,O, AU - Daidone,G, AU - Maggio,B, AU - Schillaci,D, PY - 2002/6/18/pubmed PY - 2002/7/18/medline PY - 2002/6/18/entrez SP - 3 EP - 7 JF - Bollettino chimico farmaceutico JO - Boll Chim Farm VL - 141 IS - 1 N2 - New N-(5-methylisoxazol-3-yl)-2 or 3 or 4-(phenoxyacetamido)benzamides 6a-t were synthesized and tested for their in vitro antimicrobial activity against gram positive (Staphylococcus aureus ATCC 25923) and gram negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853) bacteria as well as fungi (Candida albicans ATCC 10231, Candida tropicalis ATCC 13803 and Cryptococcus neoformans ATCC 90112). Compounds 6 were devoid of antibacterial as well as antifungal activities at maximum tested concentrations of 50 micrograms/ml for bacteria and 100 micrograms/ml for yeast. SN - 0006-6648 UR - https://www.unboundmedicine.com/medline/citation/12064055/Synthesis_and_antimicrobial_evaluation_of_new_phenoxyacetamide_derivatives_ L2 - https://medlineplus.gov/molds.html DB - PRIME DP - Unbound Medicine ER -