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[Familial pancreatic cancer--concept for study of the National Case Collection and early diagnosis program for high risk people].
Z Arztl Fortbild Qualitatssich 2002; 96(4):251-5ZA

Abstract

Ductal pancreatic cancer is a public health problem on the increase. The lethality and incidence of this disease are almost identical. A number of these cancers cluster in families. By definition, pancreatic cancer appearing in at least two first degree relatives is named familial pancreatic cancer (FPC). The "National Case Collection Familial Pancreatic Cancer" (FaPaCa) was founded at the Philipps University of Marburg, Germany, in July 1999 within the scope of the project "Clinical and genetic examinations of familial exocrine pancreatic cancer including the foundation of a national case collection" (http://www.med.uni-marburg.de/fapaca). The aims of this project are 1 to evaluate the share of FPC of all pancreatic cancers by performing a multi-centered study, 2 to identify epidemiological risk factors that predispose to pancreatic cancer in these families, 3 to identify families with a likely genetic predisposition to pancreatic cancer, 4 to offer a screening program for high risk individuals in these families, which is to be evaluated in an observational study, and finally to identify presumed genetic defects that predispose to pancreatic cancer in FPC families. This manuscript presents the scientific concept behind the FaPaCa project and reports on its attendant screening program for FPC families.

Authors+Show Affiliations

Klinik für Viszeral-, Thorax- und Gefässchirurgie, Philipps Universität Marburg.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

ger

PubMed ID

12068743

Citation

Gerdes, Berthold, et al. "[Familial Pancreatic Cancer--concept for Study of the National Case Collection and Early Diagnosis Program for High Risk People]." Zeitschrift Fur Arztliche Fortbildung Und Qualitatssicherung, vol. 96, no. 4, 2002, pp. 251-5.
Gerdes B, Kress R, Rieder H, et al. [Familial pancreatic cancer--concept for study of the National Case Collection and early diagnosis program for high risk people]. Z Arztl Fortbild Qualitatssich. 2002;96(4):251-5.
Gerdes, B., Kress, R., Rieder, H., Sina-Frey, M., Przypadlo, E., Barth, P., ... Bartsch, D. K. (2002). [Familial pancreatic cancer--concept for study of the National Case Collection and early diagnosis program for high risk people]. Zeitschrift Fur Arztliche Fortbildung Und Qualitatssicherung, 96(4), pp. 251-5.
Gerdes B, et al. [Familial Pancreatic Cancer--concept for Study of the National Case Collection and Early Diagnosis Program for High Risk People]. Z Arztl Fortbild Qualitatssich. 2002;96(4):251-5. PubMed PMID: 12068743.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Familial pancreatic cancer--concept for study of the National Case Collection and early diagnosis program for high risk people]. AU - Gerdes,Berthold, AU - Kress,Ralf, AU - Rieder,Harald, AU - Sina-Frey,Mercedes, AU - Przypadlo,Elvira, AU - Barth,Peter, AU - Rehder,Helga, AU - Hahn,Stephan A, AU - Schmiegel,Wolff, AU - Rothmund,Matthias, AU - Ziegler,Andreas, AU - Bartsch,Detlef K, PY - 2002/6/19/pubmed PY - 2002/7/26/medline PY - 2002/6/19/entrez SP - 251 EP - 5 JF - Zeitschrift fur arztliche Fortbildung und Qualitatssicherung JO - Z Arztl Fortbild Qualitatssich VL - 96 IS - 4 N2 - Ductal pancreatic cancer is a public health problem on the increase. The lethality and incidence of this disease are almost identical. A number of these cancers cluster in families. By definition, pancreatic cancer appearing in at least two first degree relatives is named familial pancreatic cancer (FPC). The "National Case Collection Familial Pancreatic Cancer" (FaPaCa) was founded at the Philipps University of Marburg, Germany, in July 1999 within the scope of the project "Clinical and genetic examinations of familial exocrine pancreatic cancer including the foundation of a national case collection" (http://www.med.uni-marburg.de/fapaca). The aims of this project are 1 to evaluate the share of FPC of all pancreatic cancers by performing a multi-centered study, 2 to identify epidemiological risk factors that predispose to pancreatic cancer in these families, 3 to identify families with a likely genetic predisposition to pancreatic cancer, 4 to offer a screening program for high risk individuals in these families, which is to be evaluated in an observational study, and finally to identify presumed genetic defects that predispose to pancreatic cancer in FPC families. This manuscript presents the scientific concept behind the FaPaCa project and reports on its attendant screening program for FPC families. SN - 1431-7621 UR - https://www.unboundmedicine.com/medline/citation/12068743/[Familial_pancreatic_cancer__concept_for_study_of_the_National_Case_Collection_and_early_diagnosis_program_for_high_risk_people]_ L2 - http://www.diseaseinfosearch.org/result/5551 DB - PRIME DP - Unbound Medicine ER -