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Abnormal esophageal acid exposure is common in morbidly obese patients and improves after a successful Lap-band system implantation.
Surg Endosc 2002; 16(11):1631-5SE

Abstract

BACKGROUND

The relation between gastro-esophageal reflux disease (GERD) and obesity is controversial. The laparoscopic adjustable gastric band (LAGB) procedure is effective for morbid obesity. Its indication in the presence of GERD, however, is still debated. This study aimed to investigate esophageal symptoms, motility patterns, and acid exposure in morbidly obese patients before and after LAGB placement.

METHOD

For this study, 43 consecutive obese patients were investigated by a standardized symptoms questionnaire, stationary manometry and 24-h ambulatory pH-metry, and 16 patients with abnormal esophageal acid exposure were reevaluated 18 months after LAGB placement.

RESULTS

Symptom scores and abnormal esophageal acid exposure were found to be significantly higher, Lower Esophageal Sphincter (LOS) pressure was significantly lower in obese patients than in control subjects. After LAGB, esophageal acid exposure was significantly reduced in all but two patients, who presented with proximal of gastric pouch dilation.

CONCLUSIONS

There is a high prevalence of GERD in the obese population. Uncomplicated LAGB placement reduces the amount of acid in these patients with abnormal esophageal acid exposure.

Authors+Show Affiliations

Dipartimento di Chirurgia Generale, Geriatrica, Oncologica e Tecnologic Avanzate e, Università Federico II, Napoli, Italy. piovino@unina.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

12073000

Citation

Iovino, P, et al. "Abnormal Esophageal Acid Exposure Is Common in Morbidly Obese Patients and Improves After a Successful Lap-band System Implantation." Surgical Endoscopy, vol. 16, no. 11, 2002, pp. 1631-5.
Iovino P, Angrisani L, Tremolaterra F, et al. Abnormal esophageal acid exposure is common in morbidly obese patients and improves after a successful Lap-band system implantation. Surg Endosc. 2002;16(11):1631-5.
Iovino, P., Angrisani, L., Tremolaterra, F., Nirchio, E., Ciannella, M., Borrelli, V., ... Ciacci, C. (2002). Abnormal esophageal acid exposure is common in morbidly obese patients and improves after a successful Lap-band system implantation. Surgical Endoscopy, 16(11), pp. 1631-5.
Iovino P, et al. Abnormal Esophageal Acid Exposure Is Common in Morbidly Obese Patients and Improves After a Successful Lap-band System Implantation. Surg Endosc. 2002;16(11):1631-5. PubMed PMID: 12073000.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Abnormal esophageal acid exposure is common in morbidly obese patients and improves after a successful Lap-band system implantation. AU - Iovino,P, AU - Angrisani,L, AU - Tremolaterra,F, AU - Nirchio,E, AU - Ciannella,M, AU - Borrelli,V, AU - Sabbatini,F, AU - Mazzacca,G, AU - Ciacci,C, Y1 - 2002/06/20/ PY - 2001/03/12/received PY - 2002/04/01/accepted PY - 2002/6/20/pubmed PY - 2002/12/31/medline PY - 2002/6/20/entrez SP - 1631 EP - 5 JF - Surgical endoscopy JO - Surg Endosc VL - 16 IS - 11 N2 - BACKGROUND: The relation between gastro-esophageal reflux disease (GERD) and obesity is controversial. The laparoscopic adjustable gastric band (LAGB) procedure is effective for morbid obesity. Its indication in the presence of GERD, however, is still debated. This study aimed to investigate esophageal symptoms, motility patterns, and acid exposure in morbidly obese patients before and after LAGB placement. METHOD: For this study, 43 consecutive obese patients were investigated by a standardized symptoms questionnaire, stationary manometry and 24-h ambulatory pH-metry, and 16 patients with abnormal esophageal acid exposure were reevaluated 18 months after LAGB placement. RESULTS: Symptom scores and abnormal esophageal acid exposure were found to be significantly higher, Lower Esophageal Sphincter (LOS) pressure was significantly lower in obese patients than in control subjects. After LAGB, esophageal acid exposure was significantly reduced in all but two patients, who presented with proximal of gastric pouch dilation. CONCLUSIONS: There is a high prevalence of GERD in the obese population. Uncomplicated LAGB placement reduces the amount of acid in these patients with abnormal esophageal acid exposure. SN - 1432-2218 UR - https://www.unboundmedicine.com/medline/citation/12073000/Abnormal_esophageal_acid_exposure_is_common_in_morbidly_obese_patients_and_improves_after_a_successful_Lap_band_system_implantation_ L2 - https://dx.doi.org/10.1007/s00464-001-9225-0 DB - PRIME DP - Unbound Medicine ER -