Tags

Type your tag names separated by a space and hit enter

Initial color change and color retention with a hydrogen peroxide bleaching strip.
Am J Dent. 2002 Feb; 15(1):3-7.AJ

Abstract

PURPOSE

A randomized, double blind clinical trial was conducted to evaluate initial color improvement and post-treatment color retention following vital bleaching with a strip-based tooth whitening system.

MATERIALS AND METHODS

After balancing for baseline color, 57 healthy adults were randomized to either whitening strips with a 5.3% hydrogen peroxide bleaching gel (Crest Whitestrips) or placebo strips without hydrogen peroxide. Maxillary and mandibular anterior teeth were treated twice daily for 30 minutes each over a 2-week period, and efficacy was measured objectively by comparing digital images of teeth collected at baseline, end-of-treatment (Week 2) and 6 months after treatment (Month 6).

RESULTS

The whitening strip group experienced a highly significant (P< 0.0001) reduction in yellow of -2.0 deltab* units versus baseline and -1.95 deltab* units versus placebo, with similar results noted for the other color parameters in the study. Most of the initial color change remained at 6 months post-treatment, with the whitening strip group continuing to demonstrate highly significant (P< 0.0001) improvements in tooth color relative to baseline and placebo. Age was found to significantly contribute to initial color improvement, with younger subjects experiencing a greater initial reduction in yellowness compared to older participants, but not to post-treatment color retention. The whitening strips were well tolerated, with minor tooth sensitivity and oral irritation representing the most common findings during treatment. There were no persistent or new treatment-related adverse events during the 6-month monitoring period.

Authors+Show Affiliations

Health Care Research Center, The Procter & Gamble Company, Mason, OH 45040-8006, USA. gerlach.rw@pg.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12074226

Citation

Gerlach, Robert W., et al. "Initial Color Change and Color Retention With a Hydrogen Peroxide Bleaching Strip." American Journal of Dentistry, vol. 15, no. 1, 2002, pp. 3-7.
Gerlach RW, Gibb RD, Sagel PA. Initial color change and color retention with a hydrogen peroxide bleaching strip. Am J Dent. 2002;15(1):3-7.
Gerlach, R. W., Gibb, R. D., & Sagel, P. A. (2002). Initial color change and color retention with a hydrogen peroxide bleaching strip. American Journal of Dentistry, 15(1), 3-7.
Gerlach RW, Gibb RD, Sagel PA. Initial Color Change and Color Retention With a Hydrogen Peroxide Bleaching Strip. Am J Dent. 2002;15(1):3-7. PubMed PMID: 12074226.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Initial color change and color retention with a hydrogen peroxide bleaching strip. AU - Gerlach,Robert W, AU - Gibb,Roger D, AU - Sagel,Paul A, PY - 2002/6/21/pubmed PY - 2002/10/10/medline PY - 2002/6/21/entrez SP - 3 EP - 7 JF - American journal of dentistry JO - Am J Dent VL - 15 IS - 1 N2 - PURPOSE: A randomized, double blind clinical trial was conducted to evaluate initial color improvement and post-treatment color retention following vital bleaching with a strip-based tooth whitening system. MATERIALS AND METHODS: After balancing for baseline color, 57 healthy adults were randomized to either whitening strips with a 5.3% hydrogen peroxide bleaching gel (Crest Whitestrips) or placebo strips without hydrogen peroxide. Maxillary and mandibular anterior teeth were treated twice daily for 30 minutes each over a 2-week period, and efficacy was measured objectively by comparing digital images of teeth collected at baseline, end-of-treatment (Week 2) and 6 months after treatment (Month 6). RESULTS: The whitening strip group experienced a highly significant (P< 0.0001) reduction in yellow of -2.0 deltab* units versus baseline and -1.95 deltab* units versus placebo, with similar results noted for the other color parameters in the study. Most of the initial color change remained at 6 months post-treatment, with the whitening strip group continuing to demonstrate highly significant (P< 0.0001) improvements in tooth color relative to baseline and placebo. Age was found to significantly contribute to initial color improvement, with younger subjects experiencing a greater initial reduction in yellowness compared to older participants, but not to post-treatment color retention. The whitening strips were well tolerated, with minor tooth sensitivity and oral irritation representing the most common findings during treatment. There were no persistent or new treatment-related adverse events during the 6-month monitoring period. SN - 0894-8275 UR - https://www.unboundmedicine.com/medline/citation/12074226/Initial_color_change_and_color_retention_with_a_hydrogen_peroxide_bleaching_strip_ DB - PRIME DP - Unbound Medicine ER -