Tags

Type your tag names separated by a space and hit enter

Polyphenols in red wines prevent NADH oxidation induced by peroxynitrite.
Ann N Y Acad Sci. 2002 May; 957:274-8.AN

Abstract

It is known that red wines have antioxidant properties owing to the presence of polyphenols and hydroxycinnamates. It has been reported that these compounds are efficient scavengers of peroxynitrite (ONOO(-)). We assayed the ONOO(-)-scavenging activity of plant polyphenols, hydroxycinnamates, and red wines using a fluormetric assay that involves the participation of ONOO(-) (200 microM) as oxidant and NADH (50-100 microM) as a target molecule. NADH oxidation was prevented by pure polyphenols and hydroxycinnamates. With the wines, the Cabernet Sauvignon showed more potent ONOO(-)-scavenging ability than the Malbecs and the blended wines. These results correlate well with the total phenol content determined by Folin-Ciocalteau assay.

Authors+Show Affiliations

Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina. lbvaldez@ffyb.uba.arNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12074980

Citation

Valdez, Laura B., et al. "Polyphenols in Red Wines Prevent NADH Oxidation Induced By Peroxynitrite." Annals of the New York Academy of Sciences, vol. 957, 2002, pp. 274-8.
Valdez LB, Actis-Goretta L, Boveris A. Polyphenols in red wines prevent NADH oxidation induced by peroxynitrite. Ann N Y Acad Sci. 2002;957:274-8.
Valdez, L. B., Actis-Goretta, L., & Boveris, A. (2002). Polyphenols in red wines prevent NADH oxidation induced by peroxynitrite. Annals of the New York Academy of Sciences, 957, 274-8.
Valdez LB, Actis-Goretta L, Boveris A. Polyphenols in Red Wines Prevent NADH Oxidation Induced By Peroxynitrite. Ann N Y Acad Sci. 2002;957:274-8. PubMed PMID: 12074980.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Polyphenols in red wines prevent NADH oxidation induced by peroxynitrite. AU - Valdez,Laura B, AU - Actis-Goretta,Lucas, AU - Boveris,Alberto, PY - 2002/6/21/pubmed PY - 2002/8/1/medline PY - 2002/6/21/entrez SP - 274 EP - 8 JF - Annals of the New York Academy of Sciences JO - Ann. N. Y. Acad. Sci. VL - 957 N2 - It is known that red wines have antioxidant properties owing to the presence of polyphenols and hydroxycinnamates. It has been reported that these compounds are efficient scavengers of peroxynitrite (ONOO(-)). We assayed the ONOO(-)-scavenging activity of plant polyphenols, hydroxycinnamates, and red wines using a fluormetric assay that involves the participation of ONOO(-) (200 microM) as oxidant and NADH (50-100 microM) as a target molecule. NADH oxidation was prevented by pure polyphenols and hydroxycinnamates. With the wines, the Cabernet Sauvignon showed more potent ONOO(-)-scavenging ability than the Malbecs and the blended wines. These results correlate well with the total phenol content determined by Folin-Ciocalteau assay. SN - 0077-8923 UR - https://www.unboundmedicine.com/medline/citation/12074980/Polyphenols_in_red_wines_prevent_NADH_oxidation_induced_by_peroxynitrite_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0077-8923&date=2002&volume=957&spage=274 DB - PRIME DP - Unbound Medicine ER -