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[Endoscopic ligation plus sclerotherapy in esophageal varices treatment. Experience in active bleeding and in the elective treatment].
Rev Med Chil. 2001 Dec; 129(12):1387-94.RM

Abstract

BACKGROUND

Endoscopic ligation is the treatment of choice for bleeding esophageal varices. The usefulness of additional sclerotherapy is not clear.

AIM

To assess the effectiveness of ligation followed by sclerotherapy in the treatment of variceal bleeding.

PATIENTS AND METHODS

Forty eight patients with variceal bleeding admitted for emergency treatment and 73 patients admitted for elective treatment were studied. Varices were ligated until a significant reduction in size was achieved. Eradication was completed with the injection of 1% polidocanol.

RESULTS

In 34 of 48 patients admitted for emergency treatment, the site of variceal rupture was identified. In all these subjects, and in 13 of 14 patients in whom the rupture site was not identified, hemorrhage was stopped with the procedure. Varices were eradicated in 108 of the 121 patients. Hemorrhage recidivated in 12.5% of patients admitted for emergency treatment, in a period of 14 months of follow up and in 9.6% of those admitted for elective treatment, in a period of 16 months follow up. Mortality was 14, 18 and 57% among patients classified as Child Pugh A, B or C, respectively.

CONCLUSIONS

Endoscopic ligation is effective in the treatment of variceal bleeding. Adding sclerotherapy, variceal eradication is achieved in a high percentage of patients. Survival depends on hepatic function.

Authors+Show Affiliations

Departamento de Gastroenterología, Servicio de Medicina, Hospital San Juan de Dios, División Occidente de la Facultad de Medicina, Universidad de Chile.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

12080876

Citation

Vargas, L, et al. "[Endoscopic Ligation Plus Sclerotherapy in Esophageal Varices Treatment. Experience in Active Bleeding and in the Elective Treatment]." Revista Medica De Chile, vol. 129, no. 12, 2001, pp. 1387-94.
Vargas L, Morales X, Ovalle L, et al. [Endoscopic ligation plus sclerotherapy in esophageal varices treatment. Experience in active bleeding and in the elective treatment]. Rev Med Chil. 2001;129(12):1387-94.
Vargas, L., Morales, X., Ovalle, L., Estay, R., & Soto, J. R. (2001). [Endoscopic ligation plus sclerotherapy in esophageal varices treatment. Experience in active bleeding and in the elective treatment]. Revista Medica De Chile, 129(12), 1387-94.
Vargas L, et al. [Endoscopic Ligation Plus Sclerotherapy in Esophageal Varices Treatment. Experience in Active Bleeding and in the Elective Treatment]. Rev Med Chil. 2001;129(12):1387-94. PubMed PMID: 12080876.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Endoscopic ligation plus sclerotherapy in esophageal varices treatment. Experience in active bleeding and in the elective treatment]. AU - Vargas,L, AU - Morales,X, AU - Ovalle,L, AU - Estay,R, AU - Soto,J R, PY - 2002/6/26/pubmed PY - 2002/8/8/medline PY - 2002/6/26/entrez SP - 1387 EP - 94 JF - Revista medica de Chile JO - Rev Med Chil VL - 129 IS - 12 N2 - BACKGROUND: Endoscopic ligation is the treatment of choice for bleeding esophageal varices. The usefulness of additional sclerotherapy is not clear. AIM: To assess the effectiveness of ligation followed by sclerotherapy in the treatment of variceal bleeding. PATIENTS AND METHODS: Forty eight patients with variceal bleeding admitted for emergency treatment and 73 patients admitted for elective treatment were studied. Varices were ligated until a significant reduction in size was achieved. Eradication was completed with the injection of 1% polidocanol. RESULTS: In 34 of 48 patients admitted for emergency treatment, the site of variceal rupture was identified. In all these subjects, and in 13 of 14 patients in whom the rupture site was not identified, hemorrhage was stopped with the procedure. Varices were eradicated in 108 of the 121 patients. Hemorrhage recidivated in 12.5% of patients admitted for emergency treatment, in a period of 14 months of follow up and in 9.6% of those admitted for elective treatment, in a period of 16 months follow up. Mortality was 14, 18 and 57% among patients classified as Child Pugh A, B or C, respectively. CONCLUSIONS: Endoscopic ligation is effective in the treatment of variceal bleeding. Adding sclerotherapy, variceal eradication is achieved in a high percentage of patients. Survival depends on hepatic function. SN - 0034-9887 UR - https://www.unboundmedicine.com/medline/citation/12080876/[Endoscopic_ligation_plus_sclerotherapy_in_esophageal_varices_treatment__Experience_in_active_bleeding_and_in_the_elective_treatment]_ L2 - https://www.diseaseinfosearch.org/result/2658 DB - PRIME DP - Unbound Medicine ER -