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Superficial endometriosis of the uterine cervix: a report of 20 cases of a process that may be confused with endocervical glandular dysplasia or adenocarcinoma in situ.
Int J Gynecol Pathol. 1999 Jul; 18(3):198-205.IJ

Abstract

Twenty cases of superficial endometriosis of the uterine cervix that occurred in patients from 20 to 51 (mean 37.1) years of age are described. The majority of the cases were seen in consultation and were usually referred because of diagnostic problems; endocervical glandular dysplasia, adenocarcinoma in situ, or rarely invasive adenocarcinoma were a frequent consideration of the contributor. The endometriosis was almost always an incidental microscopic finding. The endometriotic foci were usually confined to the superficial third of the cervical wall, but in one case there was also involvement of the middle third of the cervical wall. Deep cervical endometriosis was not present in any case. The endometriotic glands were typically evenly spaced and were surrounded at least focally by endometriotic stroma in all cases. The endometriotic stromal cells, however, were significantly obscured by inflammatory cells (two cases), inflammatory cells and hemorrhage (two cases), hemorrhage (four cases), and in one case by smooth muscle metaplasia causing initial failure to recognize the stromal component of the process. The presence of mitotic figures in the glandular epithelium contributed to an initial diagnosis of a premalignant or malignant glandular lesion being made or seriously entertained in 10 cases. Awareness that mitotic figures may be conspicuous in endometriosis from women of reproductive age, the usually bland cytologic features of the endometriotic epithelium, and the presence of associated endometrial stromal cells all facilitate establishing the correct diagnosis.

Authors+Show Affiliations

James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Department of Pathology, Harvard Medical School, Boston 02114, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12090586

Citation

Baker, P M., et al. "Superficial Endometriosis of the Uterine Cervix: a Report of 20 Cases of a Process That May Be Confused With Endocervical Glandular Dysplasia or Adenocarcinoma in Situ." International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, vol. 18, no. 3, 1999, pp. 198-205.
Baker PM, Clement PB, Bell DA, et al. Superficial endometriosis of the uterine cervix: a report of 20 cases of a process that may be confused with endocervical glandular dysplasia or adenocarcinoma in situ. Int J Gynecol Pathol. 1999;18(3):198-205.
Baker, P. M., Clement, P. B., Bell, D. A., & Young, R. H. (1999). Superficial endometriosis of the uterine cervix: a report of 20 cases of a process that may be confused with endocervical glandular dysplasia or adenocarcinoma in situ. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists, 18(3), 198-205.
Baker PM, et al. Superficial Endometriosis of the Uterine Cervix: a Report of 20 Cases of a Process That May Be Confused With Endocervical Glandular Dysplasia or Adenocarcinoma in Situ. Int J Gynecol Pathol. 1999;18(3):198-205. PubMed PMID: 12090586.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Superficial endometriosis of the uterine cervix: a report of 20 cases of a process that may be confused with endocervical glandular dysplasia or adenocarcinoma in situ. AU - Baker,P M, AU - Clement,P B, AU - Bell,D A, AU - Young,R H, PY - 2002/7/2/pubmed PY - 2002/7/23/medline PY - 2002/7/2/entrez SP - 198 EP - 205 JF - International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists JO - Int J Gynecol Pathol VL - 18 IS - 3 N2 - Twenty cases of superficial endometriosis of the uterine cervix that occurred in patients from 20 to 51 (mean 37.1) years of age are described. The majority of the cases were seen in consultation and were usually referred because of diagnostic problems; endocervical glandular dysplasia, adenocarcinoma in situ, or rarely invasive adenocarcinoma were a frequent consideration of the contributor. The endometriosis was almost always an incidental microscopic finding. The endometriotic foci were usually confined to the superficial third of the cervical wall, but in one case there was also involvement of the middle third of the cervical wall. Deep cervical endometriosis was not present in any case. The endometriotic glands were typically evenly spaced and were surrounded at least focally by endometriotic stroma in all cases. The endometriotic stromal cells, however, were significantly obscured by inflammatory cells (two cases), inflammatory cells and hemorrhage (two cases), hemorrhage (four cases), and in one case by smooth muscle metaplasia causing initial failure to recognize the stromal component of the process. The presence of mitotic figures in the glandular epithelium contributed to an initial diagnosis of a premalignant or malignant glandular lesion being made or seriously entertained in 10 cases. Awareness that mitotic figures may be conspicuous in endometriosis from women of reproductive age, the usually bland cytologic features of the endometriotic epithelium, and the presence of associated endometrial stromal cells all facilitate establishing the correct diagnosis. SN - 0277-1691 UR - https://www.unboundmedicine.com/medline/citation/12090586/Superficial_endometriosis_of_the_uterine_cervix:_a_report_of_20_cases_of_a_process_that_may_be_confused_with_endocervical_glandular_dysplasia_or_adenocarcinoma_in_situ_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=12090586.ui DB - PRIME DP - Unbound Medicine ER -