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[Treatment of alopecia areata with diphencyprone].
Rev Med Chir Soc Med Nat Iasi. 2001 Oct-Dec; 105(4):760-2.RM

Abstract

Topic immunotherapy in alopecia areata consist in a mild contact dermatitis with help of a chemical substances, with a high potency of sensitization, such as dinytroclorbenzenul (DNCB), squaric acid dibutylester (SADBE) and diphencypronil (DPCP). Eight patients with alopecia areata, 3 with mild form and 5 with severe form was treated with DPCP in acetone solution. We have obtained a positive result in 3 cases (37.5%), one with total regrows and 2 with partial regrows and a negative result in 5 cases, 3 with partial regrows and loss of the hair in other areas and 2 cases with no response after 24 weeks. We consider this method like an alternative therapy in severe alopecia areata resistant at other treatments.

Authors+Show Affiliations

Suditu G
Centrul Medical Nicolina Iaşi, Universitatea de Medicină şi Farmacie Gr.T Popa Iaşi.
Toma A
No affiliation info available
Voiculescu M
No affiliation info available

MeSH

Administration, TopicalAdolescentAdultAlopecia AreataCyclopropanesDermatitis, ContactFemaleHairHumansImmunizationMaleTreatment Outcome

Pub Type(s)

English Abstract
Journal Article

Language

rum

PubMed ID

12092234

Citation

Suditu, G, et al. "[Treatment of Alopecia Areata With Diphencyprone]." Revista Medico-chirurgicala a Societatii De Medici Si Naturalisti Din Iasi, vol. 105, no. 4, 2001, pp. 760-2.
Suditu G, Toma A, Voiculescu M. [Treatment of alopecia areata with diphencyprone]. Rev Med Chir Soc Med Nat Iasi. 2001;105(4):760-2.
Suditu, G., Toma, A., & Voiculescu, M. (2001). [Treatment of alopecia areata with diphencyprone]. Revista Medico-chirurgicala a Societatii De Medici Si Naturalisti Din Iasi, 105(4), 760-2.
Suditu G, Toma A, Voiculescu M. [Treatment of Alopecia Areata With Diphencyprone]. Rev Med Chir Soc Med Nat Iasi. 2001 Oct-Dec;105(4):760-2. PubMed PMID: 12092234.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Treatment of alopecia areata with diphencyprone]. AU - Suditu,G, AU - Toma,A, AU - Voiculescu,M, PY - 2002/7/3/pubmed PY - 2002/12/5/medline PY - 2002/7/3/entrez SP - 760 EP - 2 JF - Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi JO - Rev Med Chir Soc Med Nat Iasi VL - 105 IS - 4 N2 - Topic immunotherapy in alopecia areata consist in a mild contact dermatitis with help of a chemical substances, with a high potency of sensitization, such as dinytroclorbenzenul (DNCB), squaric acid dibutylester (SADBE) and diphencypronil (DPCP). Eight patients with alopecia areata, 3 with mild form and 5 with severe form was treated with DPCP in acetone solution. We have obtained a positive result in 3 cases (37.5%), one with total regrows and 2 with partial regrows and a negative result in 5 cases, 3 with partial regrows and loss of the hair in other areas and 2 cases with no response after 24 weeks. We consider this method like an alternative therapy in severe alopecia areata resistant at other treatments. SN - 0048-7848 UR - https://www.unboundmedicine.com/medline/citation/12092234/[Treatment_of_alopecia_areata_with_diphencyprone]_ L2 - https://www.diseaseinfosearch.org/result/313 DB - PRIME DP - Unbound Medicine ER -