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Effect of an acrylic intraocular lens with a sharp posterior optic edge on posterior capsule opacification.
J Cataract Refract Surg. 2002 Jul; 28(7):1105-11.JC

Abstract

PURPOSE

To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Sensar OptiEdge AR40e intraocular lens (IOL) (Allergan Surgical) with that of the round-edged design of the Sensar AR40 IOL. Setting Department of Ophthalmology, University of Vienna, Vienna, Austria.

METHODS

This prospective randomized patient- and examiner-masked study comprised 106 eyes of 53 patients with bilateral age-related cataract. Each patient had cataract surgery in both eyes and received an AR40 IOL in 1 eye and an AR40e IOL in the other eye. Postoperative examinations were at 1 week, 2 and 6 months, and 1 year. Digital slitlamp and digital retroillumination images of each eye were taken. The amount of PCO was assessed subjectively at the slitlamp and objectively using automated image-analysis software.

RESULTS

The AR40e group had significantly less regeneratory and fibrotic PCO 1 year after surgery. The mean automated image-analysis software PCO score (scale 0 to 10) was 2.19 in the AR40 group and 1.10 in the AR40e group (P <.001). The AR40e group had less peripheral fibrotic PCO. There was no significant difference in patient-reported edge glare between the 2 IOL groups.

CONCLUSIONS

The sharp-edged design of the Sensar OptiEdge AR40e IOL led to significantly less PCO than the round-edged AR40 IOL 1 year postoperatively.

Authors+Show Affiliations

Buehl W
Department of Ophthalmology, University of Vienna, Waehriger Guertel 18-20, 1090 Wien, Austria.
Findl O
No affiliation info available
Menapace R
No affiliation info available
Rainer G
No affiliation info available
Sacu S
No affiliation info available
Kiss B
No affiliation info available
Petternel V
No affiliation info available
Georgopoulos M
No affiliation info available

MeSH

Acrylic ResinsAgedCapsulorhexisCataractDouble-Blind MethodHumansLens Capsule, CrystallineLens Implantation, IntraocularLenses, IntraocularPhacoemulsificationPostoperative ComplicationsProspective StudiesProsthesis DesignTreatment OutcomeVisual Acuity

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

12106717

Clinical Trial Links

Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification

Citation

Buehl, Wolf, et al. "Effect of an Acrylic Intraocular Lens With a Sharp Posterior Optic Edge On Posterior Capsule Opacification." Journal of Cataract and Refractive Surgery, vol. 28, no. 7, 2002, pp. 1105-11.
Buehl W, Findl O, Menapace R, et al. Effect of an acrylic intraocular lens with a sharp posterior optic edge on posterior capsule opacification. J Cataract Refract Surg. 2002;28(7):1105-11.
Buehl, W., Findl, O., Menapace, R., Rainer, G., Sacu, S., Kiss, B., Petternel, V., & Georgopoulos, M. (2002). Effect of an acrylic intraocular lens with a sharp posterior optic edge on posterior capsule opacification. Journal of Cataract and Refractive Surgery, 28(7), 1105-11.
Buehl W, et al. Effect of an Acrylic Intraocular Lens With a Sharp Posterior Optic Edge On Posterior Capsule Opacification. J Cataract Refract Surg. 2002;28(7):1105-11. PubMed PMID: 12106717.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of an acrylic intraocular lens with a sharp posterior optic edge on posterior capsule opacification. AU - Buehl,Wolf, AU - Findl,Oliver, AU - Menapace,Rupert, AU - Rainer,Georg, AU - Sacu,Stefan, AU - Kiss,Barbara, AU - Petternel,Vanessa, AU - Georgopoulos,Michael, PY - 2002/7/11/pubmed PY - 2002/9/11/medline PY - 2002/7/11/entrez SP - 1105 EP - 11 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 28 IS - 7 N2 - PURPOSE: To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Sensar OptiEdge AR40e intraocular lens (IOL) (Allergan Surgical) with that of the round-edged design of the Sensar AR40 IOL. Setting Department of Ophthalmology, University of Vienna, Vienna, Austria. METHODS: This prospective randomized patient- and examiner-masked study comprised 106 eyes of 53 patients with bilateral age-related cataract. Each patient had cataract surgery in both eyes and received an AR40 IOL in 1 eye and an AR40e IOL in the other eye. Postoperative examinations were at 1 week, 2 and 6 months, and 1 year. Digital slitlamp and digital retroillumination images of each eye were taken. The amount of PCO was assessed subjectively at the slitlamp and objectively using automated image-analysis software. RESULTS: The AR40e group had significantly less regeneratory and fibrotic PCO 1 year after surgery. The mean automated image-analysis software PCO score (scale 0 to 10) was 2.19 in the AR40 group and 1.10 in the AR40e group (P <.001). The AR40e group had less peripheral fibrotic PCO. There was no significant difference in patient-reported edge glare between the 2 IOL groups. CONCLUSIONS: The sharp-edged design of the Sensar OptiEdge AR40e IOL led to significantly less PCO than the round-edged AR40 IOL 1 year postoperatively. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/12106717/Effect_of_an_acrylic_intraocular_lens_with_a_sharp_posterior_optic_edge_on_posterior_capsule_opacification_ DB - PRIME DP - Unbound Medicine ER -