TY - JOUR T1 - Clinical results 6 to 8 years after truncal vagotomy and drainage for duodenal ulcer in 500 patients. A1 - Kronborg,O, PY - 1975/1/1/pubmed PY - 1975/1/1/medline PY - 1975/1/1/entrez SP - 657 EP - 63 JF - Acta chirurgica Scandinavica JO - Acta Chir Scand VL - 141 IS - 7 N2 - The clinical results of truncal vagotomy and drainage for duodenal ulcer in 500 patients are evaluated by a personal 6-8 year follow up. Pyloroplasty was used unless pyloric stenosis made a gastrojejunostomy necessary. Forty-three patients had recurrence (39 were reoperated) and gastric ulcer was seen in five. The rate of dumping was 24% (severe in 3%) and rate of daily-monthly diarrhoea 40% (severe in 8%). Neither dumping nor diarrhoea was related to histamine-activated gastric acid secretion ten days after vagotomy and insulin-activated acid secretion 3 to 4 years later. Dumping was related to epigastric fullness and diarrhoea. Recurrence was related to histamine-activated secretion before and 10 days after vagotomy and to insulin-activated secretion 10 days and 3-4 days after vagotomy. Minor changes were seen in weight- and laboratory-measurements. Anemia was not related to prophylactic intake of iron. Satisfactory results (Visick I-III) were seen in 80% of the patients. The figure may be increased to 86%, including results of operations for recurrence, gastric ulcer and other diseases occurring after the original vagotomy and drainage; even then, the results seem less satisfactory than those after other operations for duodenal ulcer. SN - 0001-5482 UR - https://www.unboundmedicine.com/medline/citation/1211038/Clinical_results_6_to_8_years_after_truncal_vagotomy_and_drainage_for_duodenal_ulcer_in_500_patients_ DB - PRIME DP - Unbound Medicine ER -