Tags

Type your tag names separated by a space and hit enter

Cigarette and alcohol consumption and the risk of colorectal cancer in Shanghai, China.
Eur J Cancer Prev. 2002 Jun; 11(3):237-44.EJ

Abstract

The relation of cigarette smoking and alcohol drinking to colorectal cancer risk has been inconsistent in the epidemiological literature. In a population-based case-control study of colorectal cancer in Shanghai, China, where the incidence rates are rising sharply, we examined the association with tobacco and alcohol use. Cases were aged 30-74 years and newly diagnosed with cancers of the colon (N = 931) or rectum (N = 874) between 1990 and 1992. Controls (N = 1552) were randomly selected among Shanghai residents, frequency-matched to cases by gender and age. Information on lifetime consumption of tobacco and alcohol, as well as demographic and other risk factors, was obtained through in-person interviews. Associations with cigarette smoking and alcohol use were estimated by odds ratios (ORs) and 95% confidence intervals (CIs). Among women, the prevalence of smoking and alcohol drinking was low, and no significant association with colon or rectal cancer was observed. Although cigarette smoking among men was not related overall to colon or rectal cancer risk, there was a 50% excess risk of rectal cancer (OR 1.5, 95% CI 0.9-2.5) among those who smoked 55 or more pack-years. Among men, former alcohol drinkers had an increased risk of colon cancer (OR 2.3, 95% CI 1.4-3.7) but not rectal cancer, while current drinkers had a 30-50% excess risk of colon cancer only among those with long-term (30+ years) and heavy (>560 g ethanol/week) consumption. The excess risks were mainly associated with hard liquor consumption, with no material difference in risk between proximal and distal colon cancer. Although cigarette smoking and alcohol drinking in general were not risk factors for colorectal cancers in Shanghai, there were small excess risks for rectal cancer among heavy smokers and colon cancer among heavy drinkers.

Authors+Show Affiliations

Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., EPS 8120, Bethesda, MD 20852, USA. jib@exchange.nih.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

12131657

Citation

Ji, B-T, et al. "Cigarette and Alcohol Consumption and the Risk of Colorectal Cancer in Shanghai, China." European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), vol. 11, no. 3, 2002, pp. 237-44.
Ji BT, Dai Q, Gao YT, et al. Cigarette and alcohol consumption and the risk of colorectal cancer in Shanghai, China. Eur J Cancer Prev. 2002;11(3):237-44.
Ji, B. T., Dai, Q., Gao, Y. T., Hsing, A. W., McLaughlin, J. K., Fraumeni, J. F., & Chow, W. H. (2002). Cigarette and alcohol consumption and the risk of colorectal cancer in Shanghai, China. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), 11(3), 237-44.
Ji BT, et al. Cigarette and Alcohol Consumption and the Risk of Colorectal Cancer in Shanghai, China. Eur J Cancer Prev. 2002;11(3):237-44. PubMed PMID: 12131657.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cigarette and alcohol consumption and the risk of colorectal cancer in Shanghai, China. AU - Ji,B-T, AU - Dai,Q, AU - Gao,Y-T, AU - Hsing,A W, AU - McLaughlin,J K, AU - Fraumeni,J F,Jr AU - Chow,W-H, PY - 2002/7/20/pubmed PY - 2003/6/21/medline PY - 2002/7/20/entrez SP - 237 EP - 44 JF - European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) JO - Eur J Cancer Prev VL - 11 IS - 3 N2 - The relation of cigarette smoking and alcohol drinking to colorectal cancer risk has been inconsistent in the epidemiological literature. In a population-based case-control study of colorectal cancer in Shanghai, China, where the incidence rates are rising sharply, we examined the association with tobacco and alcohol use. Cases were aged 30-74 years and newly diagnosed with cancers of the colon (N = 931) or rectum (N = 874) between 1990 and 1992. Controls (N = 1552) were randomly selected among Shanghai residents, frequency-matched to cases by gender and age. Information on lifetime consumption of tobacco and alcohol, as well as demographic and other risk factors, was obtained through in-person interviews. Associations with cigarette smoking and alcohol use were estimated by odds ratios (ORs) and 95% confidence intervals (CIs). Among women, the prevalence of smoking and alcohol drinking was low, and no significant association with colon or rectal cancer was observed. Although cigarette smoking among men was not related overall to colon or rectal cancer risk, there was a 50% excess risk of rectal cancer (OR 1.5, 95% CI 0.9-2.5) among those who smoked 55 or more pack-years. Among men, former alcohol drinkers had an increased risk of colon cancer (OR 2.3, 95% CI 1.4-3.7) but not rectal cancer, while current drinkers had a 30-50% excess risk of colon cancer only among those with long-term (30+ years) and heavy (>560 g ethanol/week) consumption. The excess risks were mainly associated with hard liquor consumption, with no material difference in risk between proximal and distal colon cancer. Although cigarette smoking and alcohol drinking in general were not risk factors for colorectal cancers in Shanghai, there were small excess risks for rectal cancer among heavy smokers and colon cancer among heavy drinkers. SN - 0959-8278 UR - https://www.unboundmedicine.com/medline/citation/12131657/Cigarette_and_alcohol_consumption_and_the_risk_of_colorectal_cancer_in_Shanghai_China_ L2 - https://doi.org/10.1097/00008469-200206000-00007 DB - PRIME DP - Unbound Medicine ER -