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EEG differences between good and poor responders to methylphenidate in boys with the inattentive type of attention-deficit/hyperactivity disorder.
Clin Neurophysiol 2002; 113(8):1191-8CN

Abstract

OBJECTIVES

This study investigated electroencephalographic (EEG) differences between good and poor responders to methylphenidate in boys with the Inattentive type of Attention-Deficit/Hyperactivity Disorder (ADHD).

METHODS

Twenty good and 15 poor responders to methylphenidate, based on the results of a continuous performance task, and 35 age- and sex-matched control subjects, participated in this study. EEG was recorded from 21 sites during an eyes-closed resting condition and Fourier transformed to provide estimates for total power, and absolute and relative power in the delta, theta, alpha and beta bands, and for the theta/alpha and theta/beta ratios.

RESULTS

EEG differences were found between the ADHD children and controls which were compatible with previous literature on the Inattentive type. Differences were also found between the good and poor responders to methylphenidate.

CONCLUSIONS

Good responders had EEG profiles that suggested that they were more cortically hypoaroused than poor responders.

Authors+Show Affiliations

Brain and Behaviour Research Institute and Department of Psychology, University of Wollongong, 2522, Wollongong, Australia. adam_clarke@uow.edu.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

12139997

Citation

Clarke, Adam R., et al. "EEG Differences Between Good and Poor Responders to Methylphenidate in Boys With the Inattentive Type of Attention-deficit/hyperactivity Disorder." Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, vol. 113, no. 8, 2002, pp. 1191-8.
Clarke AR, Barry RJ, McCarthy R, et al. EEG differences between good and poor responders to methylphenidate in boys with the inattentive type of attention-deficit/hyperactivity disorder. Clin Neurophysiol. 2002;113(8):1191-8.
Clarke, A. R., Barry, R. J., McCarthy, R., Selikowitz, M., & Croft, R. J. (2002). EEG differences between good and poor responders to methylphenidate in boys with the inattentive type of attention-deficit/hyperactivity disorder. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, 113(8), pp. 1191-8.
Clarke AR, et al. EEG Differences Between Good and Poor Responders to Methylphenidate in Boys With the Inattentive Type of Attention-deficit/hyperactivity Disorder. Clin Neurophysiol. 2002;113(8):1191-8. PubMed PMID: 12139997.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - EEG differences between good and poor responders to methylphenidate in boys with the inattentive type of attention-deficit/hyperactivity disorder. AU - Clarke,Adam R, AU - Barry,Robert J, AU - McCarthy,Rory, AU - Selikowitz,Mark, AU - Croft,Rodney J, PY - 2002/7/26/pubmed PY - 2002/9/21/medline PY - 2002/7/26/entrez SP - 1191 EP - 8 JF - Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology JO - Clin Neurophysiol VL - 113 IS - 8 N2 - OBJECTIVES: This study investigated electroencephalographic (EEG) differences between good and poor responders to methylphenidate in boys with the Inattentive type of Attention-Deficit/Hyperactivity Disorder (ADHD). METHODS: Twenty good and 15 poor responders to methylphenidate, based on the results of a continuous performance task, and 35 age- and sex-matched control subjects, participated in this study. EEG was recorded from 21 sites during an eyes-closed resting condition and Fourier transformed to provide estimates for total power, and absolute and relative power in the delta, theta, alpha and beta bands, and for the theta/alpha and theta/beta ratios. RESULTS: EEG differences were found between the ADHD children and controls which were compatible with previous literature on the Inattentive type. Differences were also found between the good and poor responders to methylphenidate. CONCLUSIONS: Good responders had EEG profiles that suggested that they were more cortically hypoaroused than poor responders. SN - 1388-2457 UR - https://www.unboundmedicine.com/medline/citation/12139997/EEG_differences_between_good_and_poor_responders_to_methylphenidate_in_boys_with_the_inattentive_type_of_attention_deficit/hyperactivity_disorder_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1388245702001475 DB - PRIME DP - Unbound Medicine ER -