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Balo's concentric sclerosis. Evolution of active demyelination demonstrated by serial contrast-enhanced MRI.
J Neurol. 2002 Jul; 249(7):811-4.JN

Abstract

We report a case of Balo's concentric sclerosis with peculiar MRI findings. Unlike previously published cases all concentric rings in our case showed marked enhancement, supporting the view of synchronous active demyelination in the lesion. Follow-up MRI disclosed a change of the lesions into a confluent pattern more resembling a typical large MS plaque. There were no oligoclonal bands or intrathecal Ig-G synthesis. The hypothesis concerning the pathophysiology of the lesions' typical and peculiar morphological appearance and its relationship to multiple sclerosis are briefly discussed.

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Authors+Show Affiliations

Kastrup O
Neurologische Universitätsklinik, Hufelandstr. 55, 45122 Essen, Germany. oliver.kastrup@uni-essen.de
Stude P
No affiliation info available
Limmroth V
No affiliation info available

MeSH

AdultDiffuse Cerebral Sclerosis of SchilderDisease ProgressionGadoliniumHumansMagnetic Resonance ImagingMaleMultiple SclerosisRecurrence

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

12140661

Citation

Kastrup, O, et al. "Balo's Concentric Sclerosis. Evolution of Active Demyelination Demonstrated By Serial Contrast-enhanced MRI." Journal of Neurology, vol. 249, no. 7, 2002, pp. 811-4.
Kastrup O, Stude P, Limmroth V. Balo's concentric sclerosis. Evolution of active demyelination demonstrated by serial contrast-enhanced MRI. J Neurol. 2002;249(7):811-4.
Kastrup, O., Stude, P., & Limmroth, V. (2002). Balo's concentric sclerosis. Evolution of active demyelination demonstrated by serial contrast-enhanced MRI. Journal of Neurology, 249(7), 811-4.
Kastrup O, Stude P, Limmroth V. Balo's Concentric Sclerosis. Evolution of Active Demyelination Demonstrated By Serial Contrast-enhanced MRI. J Neurol. 2002;249(7):811-4. PubMed PMID: 12140661.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Balo's concentric sclerosis. Evolution of active demyelination demonstrated by serial contrast-enhanced MRI. AU - Kastrup,O, AU - Stude,P, AU - Limmroth,V, PY - 2002/7/26/pubmed PY - 2002/9/26/medline PY - 2002/7/26/entrez SP - 811 EP - 4 JF - Journal of neurology JO - J Neurol VL - 249 IS - 7 N2 - We report a case of Balo's concentric sclerosis with peculiar MRI findings. Unlike previously published cases all concentric rings in our case showed marked enhancement, supporting the view of synchronous active demyelination in the lesion. Follow-up MRI disclosed a change of the lesions into a confluent pattern more resembling a typical large MS plaque. There were no oligoclonal bands or intrathecal Ig-G synthesis. The hypothesis concerning the pathophysiology of the lesions' typical and peculiar morphological appearance and its relationship to multiple sclerosis are briefly discussed. SN - 0340-5354 UR - https://www.unboundmedicine.com/medline/citation/12140661/Balo's_concentric_sclerosis__Evolution_of_active_demyelination_demonstrated_by_serial_contrast_enhanced_MRI_ L2 - https://dx.doi.org/10.1007/s00415-002-0718-0 DB - PRIME DP - Unbound Medicine ER -