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Critical factors for bone health in women across the age span: how important is muscle mass?
Medscape Womens Health. 2002 May-Jun; 7(3):2.MW

Abstract

OBJECTIVES/DESIGN

This cross-sectional study of 113 healthy white women, 20-88 years of age, evaluated relationships between bone mineral density (BMD), body composition, calcium (Ca) intake, and physical activity. The analysis was performed in the entire cohort and in groups divided by reproductive/menopausal status (premenopausal, perimenopausal, early postmenopausal, and late postmenopausal).

METHODS

BMD and body composition were measured with Lunar DPX-MD densitometer using specialized software for total body, spine, femur, and forearm. Ca intake from food and supplements was assessed by a food frequency questionnaire. Past physical activity and past and present walking were assessed only in the older cohort using modified version of the Allied Dunbar National Fitness Survey for Older Adults.

RESULTS

The results showed significant reduction of both total body BMD and lean body mass (LBM) of 13% and 12%, respectively, with age. LBM was the strongest determinant of BMD in various skeletal sites in the entire cohort and groups. Ca was positively associated with BMD of various regions of hip in the entire cohort and in the youngest and oldest subjects (r ranging from 0.32-0.56, P <.05, in simple regression), but not in perimenopausal and early postmenopausal women. Past activity (sports and recreation) was positively associated with BMD in total body, spine, hip, and forearm (r ranging from 0.26-0.37, P <.05). Various modes of present walking were positively associated with BMD in regions of femur and forearm.

CONCLUSIONS

These results reveal the importance of lean tissue acting independently on bone at different skeletal sites in women across age groups as well as the positive effects on BMD of Ca in the youngest and oldest women and life-long engagement in physical activity in older women.

Authors+Show Affiliations

School of Allied Health, University of Connecticut, Storrs, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

12142855

Citation

Ilich-Ernst, Jasminka, et al. "Critical Factors for Bone Health in Women Across the Age Span: How Important Is Muscle Mass?" Medscape Women's Health, vol. 7, no. 3, 2002, p. 2.
Ilich-Ernst J, Brownbill RA, Ludemann MA, et al. Critical factors for bone health in women across the age span: how important is muscle mass? Medscape Womens Health. 2002;7(3):2.
Ilich-Ernst, J., Brownbill, R. A., Ludemann, M. A., & Fu, R. (2002). Critical factors for bone health in women across the age span: how important is muscle mass? Medscape Women's Health, 7(3), 2.
Ilich-Ernst J, et al. Critical Factors for Bone Health in Women Across the Age Span: How Important Is Muscle Mass. Medscape Womens Health. 2002 May-Jun;7(3):2. PubMed PMID: 12142855.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Critical factors for bone health in women across the age span: how important is muscle mass? AU - Ilich-Ernst,Jasminka, AU - Brownbill,Rhonda A, AU - Ludemann,Martha A, AU - Fu,Rongwei, PY - 2002/7/27/pubmed PY - 2002/8/7/medline PY - 2002/7/27/entrez SP - 2 EP - 2 JF - Medscape women's health JO - Medscape Womens Health VL - 7 IS - 3 N2 - OBJECTIVES/DESIGN: This cross-sectional study of 113 healthy white women, 20-88 years of age, evaluated relationships between bone mineral density (BMD), body composition, calcium (Ca) intake, and physical activity. The analysis was performed in the entire cohort and in groups divided by reproductive/menopausal status (premenopausal, perimenopausal, early postmenopausal, and late postmenopausal). METHODS: BMD and body composition were measured with Lunar DPX-MD densitometer using specialized software for total body, spine, femur, and forearm. Ca intake from food and supplements was assessed by a food frequency questionnaire. Past physical activity and past and present walking were assessed only in the older cohort using modified version of the Allied Dunbar National Fitness Survey for Older Adults. RESULTS: The results showed significant reduction of both total body BMD and lean body mass (LBM) of 13% and 12%, respectively, with age. LBM was the strongest determinant of BMD in various skeletal sites in the entire cohort and groups. Ca was positively associated with BMD of various regions of hip in the entire cohort and in the youngest and oldest subjects (r ranging from 0.32-0.56, P <.05, in simple regression), but not in perimenopausal and early postmenopausal women. Past activity (sports and recreation) was positively associated with BMD in total body, spine, hip, and forearm (r ranging from 0.26-0.37, P <.05). Various modes of present walking were positively associated with BMD in regions of femur and forearm. CONCLUSIONS: These results reveal the importance of lean tissue acting independently on bone at different skeletal sites in women across age groups as well as the positive effects on BMD of Ca in the youngest and oldest women and life-long engagement in physical activity in older women. SN - 1521-2076 UR - https://www.unboundmedicine.com/medline/citation/12142855/Critical_factors_for_bone_health_in_women_across_the_age_span:_how_important_is_muscle_mass L2 - http://www.medscape.com/viewarticle/432910 DB - PRIME DP - Unbound Medicine ER -