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Clinical presentation of microbial keratitis with daily wear frequent-replacement hydrogel lenses: a case series.
CLAO J. 2002 Jul; 28(3):165-8.CJ

Abstract

Microbial keratitis (MK) is a serious complication associated with contact lens wear. In this case series we report three clinical presentations of MK associated with daily-wear monthly-replacement soft contact lenses. All of these patients were using vifilcon A (55% water content, ionic, U.S. Food and Drug Administration [FDA] group IV) monthly-replacement soft contact lenses. A gram-stained smear of the corneal scrapings of two patients showed numerous gram-negative cocci bacilli, and tissue cultures showed significant growth of Pseudomonas aeruginosa. In the third patient, the corneal scrapings showed numerous gram-negative bacilli, along with gram-positive cocci, and tissue culture showed significant growth of Aeromonas species and alpha-hemolytic streptococci. All these cases were resolved by medical therapy. This case series highlights the importance of patient symptoms, clinical features, and microbiologic work-up in making a differentiation between MK and sterile contact lens-induced peripheral ulcer (CLPU). A high index of suspicion and close follow-up care will avoid misdiagnosis and reduce complications.

Authors+Show Affiliations

Bausch & Lomb Contact Lens Center, L.V. Prasad Eye Institute, Hyderabad, India. konda@lvpeye.stph.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

12144239

Citation

Venkata, Nagaraju, et al. "Clinical Presentation of Microbial Keratitis With Daily Wear Frequent-replacement Hydrogel Lenses: a Case Series." The CLAO Journal : Official Publication of the Contact Lens Association of Ophthalmologists, Inc, vol. 28, no. 3, 2002, pp. 165-8.
Venkata N, Sharma S, Gora R, et al. Clinical presentation of microbial keratitis with daily wear frequent-replacement hydrogel lenses: a case series. CLAO J. 2002;28(3):165-8.
Venkata, N., Sharma, S., Gora, R., Chhabra, R., & Aasuri, M. K. (2002). Clinical presentation of microbial keratitis with daily wear frequent-replacement hydrogel lenses: a case series. The CLAO Journal : Official Publication of the Contact Lens Association of Ophthalmologists, Inc, 28(3), 165-8.
Venkata N, et al. Clinical Presentation of Microbial Keratitis With Daily Wear Frequent-replacement Hydrogel Lenses: a Case Series. CLAO J. 2002;28(3):165-8. PubMed PMID: 12144239.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical presentation of microbial keratitis with daily wear frequent-replacement hydrogel lenses: a case series. AU - Venkata,Nagaraju, AU - Sharma,Savitri, AU - Gora,Rashmi, AU - Chhabra,Rajni, AU - Aasuri,Murali K, PY - 2002/7/30/pubmed PY - 2003/1/8/medline PY - 2002/7/30/entrez SP - 165 EP - 8 JF - The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc JO - CLAO J VL - 28 IS - 3 N2 - Microbial keratitis (MK) is a serious complication associated with contact lens wear. In this case series we report three clinical presentations of MK associated with daily-wear monthly-replacement soft contact lenses. All of these patients were using vifilcon A (55% water content, ionic, U.S. Food and Drug Administration [FDA] group IV) monthly-replacement soft contact lenses. A gram-stained smear of the corneal scrapings of two patients showed numerous gram-negative cocci bacilli, and tissue cultures showed significant growth of Pseudomonas aeruginosa. In the third patient, the corneal scrapings showed numerous gram-negative bacilli, along with gram-positive cocci, and tissue culture showed significant growth of Aeromonas species and alpha-hemolytic streptococci. All these cases were resolved by medical therapy. This case series highlights the importance of patient symptoms, clinical features, and microbiologic work-up in making a differentiation between MK and sterile contact lens-induced peripheral ulcer (CLPU). A high index of suspicion and close follow-up care will avoid misdiagnosis and reduce complications. SN - 0733-8902 UR - https://www.unboundmedicine.com/medline/citation/12144239/Clinical_presentation_of_microbial_keratitis_with_daily_wear_frequent_replacement_hydrogel_lenses:_a_case_series_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=12144239.ui DB - PRIME DP - Unbound Medicine ER -